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Rocuronium (category Neuromuscular blockers)
Butterworth IV, John F.; Mackey, David C.; Wasnick, John D. (2022), "Neuromuscular Blocking Agents", Morgan & Mikhail’s Clinical Anesthesiology (7 ed.), New

2 KB (86 words) - 14:27, 22 December 2022
Vecuronium (category Neuromuscular blockers)
clinical practice Lien, Cynthia A.; Eikermann, Matthias (2013), "Neuromuscular Blockers and Reversal Drugs", Pharmacology and Physiology for Anesthesia

5 KB (420 words) - 09:10, 5 January 2023
Succinylcholine (category Neuromuscular blockers)
Succinylcholine, also known as suxamethonium, is a short-acting neuromuscular blocker used during intubation. hyperkalemia increased risk of malignant

2 KB (25 words) - 16:41, 17 July 2022
Mivacurium (category Neuromuscular blockers)
in the United States of America Goodwin, G., Joseph, V. (2015). Neuromuscular Blockers. In: Kaye, A., Kaye, A., Urman, R. (eds) Essentials of Pharmacology

6 KB (503 words) - 09:28, 5 January 2023
Table of contents (section Neuromuscular blockers)
Brachial plexus blocks Interscalene block Supraclavicular block Infraclavicular block Axillary block Digital block Wrist block Intercostal nerve block Pectoralis

48 KB (3,882 words) - 14:34, 16 August 2023
Cisatracurium (category Neuromuscular blockers)
retrieved 2023-01-05 Lien, Cynthia A.; Eikermann, Matthias (2013), "Neuromuscular Blockers and Reversal Drugs", Pharmacology and Physiology for Anesthesia

5 KB (449 words) - 14:14, 8 January 2023
Myasthenia gravis (section Neuromuscular blockade)
to nondepolarizing neuromuscular blockers Resistant to succinylcholine At increased risk for developing phase II neuromuscular block, particularly with

6 KB (544 words) - 04:57, 17 July 2022
Amyotrophic lateral sclerosis
disease may incite hyperkalemia after administration Non-depolarizing neuromuscular blockers may be prolonged Take caution with regional anesthesia, although

3 KB (171 words) - 05:51, 14 June 2023
Pharmacogenetics and pharmacogenomics (section Neuromuscular blockers)
In those patients who are heterozygous for Asp70Gly, the effects of neuromuscular blockade may be prolonged three to eight times that of normal3. In those

18 KB (2,664 words) - 19:49, 4 October 2022
Sugammadex (category Neuromuscular blocker reversal agents)
Sugammadex Sugammadex is used to reverse neuromuscular blockade from rocuronium and vecuronium. If a patient requires reparaylsis after administration

3 KB (161 words) - 00:34, 30 March 2022
Antibiotics
reaction, not anaphylaxis Allergic reactions are more likely from neuromuscular blockers than antibiotics From Vaisman, et al. JAMA 2017 Patients at increased

10 KB (1,348 words) - 11:29, 1 September 2023
Vagus nerve stimulation
preferred for rapid emergence to facilitate early neuro exam. Patient neuromuscularly blocked throughout to reduce risk of inadvertent injury. No neuromonitoring

4 KB (82 words) - 17:59, 31 July 2022
Neuromuscular blockade
Neuromuscular blockade involves the use of neuromuscular blocking agents (NMBAs) (i.e. paralytics) to facilitate endotracheal intubation and/or surgical

8 KB (1,025 words) - 04:45, 4 July 2022
Atracurium
Clinical data Drug class Neuromuscular blocker Routes of administration Intravenous Dosage Pharmacodynamics Mechanism of action Nicotinic acetylcholine

1 KB (9 words) - 00:32, 30 March 2022
Pancuronium
Clinical data Drug class Neuromuscular blocker Dosage Pharmacodynamics Mechanism of action Nicotinic acetylcholine antagonism Pharmacokinetics Physical

1 KB (9 words) - 00:33, 30 March 2022
Liver transplant
(low albumin level), and increased sensitivity. Non depolarizing neuromuscular blocking agents should be chosen with patients organ function in mind. Often

24 KB (969 words) - 22:28, 14 January 2024
Tetralogy of Fallot/Pulmonary Atresia/Major Aortopulmonary Collateral Arteries
ketamine, or dexmedetomidine with a longer acting nondepolarizing neuromuscular blocker infusion. Tend to avoid propofol due to risk of interfering with

7 KB (731 words) - 12:21, 4 May 2024

File:Suggested reading neuro ABR.pdf (matches file content)

Characterization of the interactions between volatile anesthetics and neuromuscular blockers at the muscle nicotinic acetylcholine receptor. Anesth Analg. 2002

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File:Awake Fiberoptic Intubation 2018 6 (002).pdf (matches file content)

using appropriate anesthetic agents (intravenous, inhalational, neuromuscular blockers). 3

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File:Goligher Anesthesiology 2017 - Synchrony and MV.pdf (matches file content)

Guérin C, Prat G, Morange S, Roch A; ACURASYS Study Investigators: Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med 2010;

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Category:Neuromuscular blocker reversal agents

1 member (0 subcategories, 0 files) - 09:18, 20 February 2021

File:Dres Intensive Care Med 2017 - Critical Illness Diaphragm Atrophy.pdf (matches file content)

guided by judicious evaluation of expected benefits and harm. While neuromuscular blockers are used to adapt patients to the ventilator, they render the diaphragm

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File:Shaydenfish et al reversal AnesthAnalg 2019.pdf (matches file content)

primary hypothesis that neuromuscular blocking drug reversal with neostigmine and glycopyrrolate versus no neuromuscular blocking drug reversal is associated

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File:Gattinoni AMA 2018 - Re-think approach to ARDS.pdf (matches file content)

Papazian L, Forel JM, Gacouin A, et al; ACURASYS Study Investigators. Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med. 2010;363(12):1107-1116

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File:Residual neuromuscular blockade and paralysis and negative perioperative outcomes -review- (Farhan 2014).pdf (matches file content)

paralysis such as neuromuscular transmission monitoring and judicious use of low-dose neuromuscular blocking drugs. Neuromuscular blocking agent effects should

(1,240 × 1,647 (616 KB)) - 00:32, 17 May 2022

File:Intraoperative neuromuscular monitoring site and residual paralysis (Thilen 2012).pdf (matches file content)

intense neuromuscular block. Anesth Analg 1994; 78:697-700 13. Rimaniol JM, Dhonneur G, Sperry L, Duvaldestin P: A comparison of the neuromuscular blocking

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Small bowel resection
gastric decompression prior to insufflation, if laparoscopic. Maintain neuromuscular blockade with ToF assessment. If the patient has an epidural catheter

6 KB (793 words) - 12:43, 22 September 2022
Atropine
for reversal of neuromuscular blockade in order to reduce their muscarinic effects. Treatment of bradycardia (vasovagal response, AV block, bradyarrhythmias)

6 KB (510 words) - 18:18, 10 January 2024

File:Obstetric Anesthesia CA1 Lecture 05Feb21.pdf (matches file content)

volatile anesthetics • Increased sensitivity of nondepolarizing neuromuscular blockers • Increased risk of pulmonary edema 8-12 mEq/L • Loss of deep tendon

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File:Brochard PSILI.pdf (matches file content)

JM, Perez D, Seghboyan JM, et al.; ACURASYS Study Investigators. Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med 2010;363:

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File:Sottile ATS 2017 - Cisatracurium vs Vecuronium.pdf (matches file content)

VASOPRESSOR DAYS PRIOR TO NEUROMUSCULAR BLOCKADE RENAL FAILURE DATS PRIOR TO NEUROMUSCULAR BLOCKADE DAYS FROM VENTILATION TO NEUROMUSCULAR BLOCKADE PROPENSITY

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File:Ruscic 2017 Curr Opin Anes - Respiratory Complications.pdf (matches file content)

neostigmine reversal using neuromuscular transmission monitoring. 32. Berg H, Roed J, Viby-Mogensen J, et al. Residual neuromuscular block is a risk factor for

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File:Obstetric Anesthesia Review for the Basic Boards 08May18.pdf (matches file content)

following regional nerve blocks except a. b. c. d. e. Paracervical block Saddle block Lumbar epidural block Pudendal block Caudal block Somatic pain associated

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File:CSI Checklist 2020.pdf (matches file content)

Workstation principles ☐ Emergency push medications: ☐ Vasopressor ☐ Rapid Neuromuscular blocker ☐ Induction agent ☐ Laryngoscopes ☐ Oral airway ☐ Endotracheal Tube

(1,275 × 1,650 (78 KB)) - 00:34, 17 May 2022

File:APFS Startup Checklist .pdf (matches file content)

to complete the startup-test as safely as possible. 1) Administer neuromuscular blocker and/or sedation to prevent patient coughing 2) Have ready, a metal

(1,275 × 1,650 (131 KB)) - 00:38, 17 May 2022

File:Anaphylaxis Advanced Topics in Anesthesia March 2018.pdf (matches file content)

and Interventions IV. Causes of Anaphylaxis A. Neuromuscular blocking drugs Neuromuscular blocking drugs (NMBDs) have long been considered the most common

(1,275 × 1,650 (167 KB)) - 00:30, 17 May 2022

Brugada syndrome (section Neuromuscular blockade)
(primarily class 1A and 1C antiarrhythmics) Sugammadex should be used for neuromuscular blockade reversal Manage arrhythmic storm with defibrillation, isoprotenerol

19 KB (2,301 words) - 23:40, 11 November 2022
Carotid endarterectomy
premedication. Superficial cervical plexus blocks + supplemental field blocks by surgeon Deep cervical plexus blocks are now avoided due to concomitant Horner's

13 KB (1,149 words) - 17:50, 21 July 2022
Endovascular aortic repair
Most common anesthesia type is general anesthesia May need to reverse neuromuscular blockade if neuromonitoring is used If neuraxial anesthesia is chosen

11 KB (878 words) - 22:45, 21 February 2022

File:Breastfeeding.pdf (matches file content)

Vitamins in Nitrous Oxide trial, serial IV = intravenous; NMBAs = neuromuscular blocking agents. postoperative 12-lead ECG were obtained from 469 patients

(1,218 × 1,631 (351 KB)) - 10:51, 26 July 2021

File:ART Investigators Am Med Assoc 2017 - Rm and survival in ards.pdf (matches file content)

not significantly different after day 1. Cointerventions Use of neuromuscular blockers was higher in the experimental than the control group (96.8% vs

(1,275 × 1,650 (442 KB)) - 00:32, 17 May 2022

File:Lele J of Clinical Anes 2013 - Severe hypothyroidism myxedema coma in post op period.pdf (matches file content)

metabolic derangements, and drug interactions with calcium channel blockers, beta-blockers, angiotensin-converting enzyme inhibitors, and 5HT-3 agents. Caution

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Arteriovenous access for hemodialysis
Supraclavicular block supplemented with intercostobrachial nerve field block Infraclavicular block supplemented with intercostobrachial nerve field block Standard

8 KB (438 words) - 01:02, 5 April 2022
Hip arthroplasty
fascia iliaca lumbar ESP (Erector spinae plane) block PENG Block (Pericapsular Nerve Group Block/Hip Block) Standard ASA monitoring. Consider addition of

26 KB (2,419 words) - 11:09, 12 July 2023
Myomectomy
neuraxial for analgesic Consider TIVA is high risk for PONV Maintain neuromuscular blockade if open or laparoscopy Physiology of abdominal insufflation

7 KB (443 words) - 18:09, 30 June 2022

File:Chapter 71 Allergy and Anaphylaxis - Critical Care Secrets May 2017.pdf (matches file content)

enzyme inhibitors. Causes of Anaphylaxis 8. How frequently do neuromuscular blocking drugs (NMBDs) cause anaphylaxis, and what is the mechanism? NMBDs

(1,275 × 1,650 (161 KB)) - 00:41, 17 May 2022

Shoulder arthroplasty
ensure adequate cerebral perfusion in upright position Maintenance of neuromuscular blockade may be helpful for surgeons Monitor for venous air embolus,

7 KB (353 words) - 15:21, 13 June 2022

File:APFS Quick Reference - Anes Vent as ICU Vent.pdf (matches file content)

to complete the startup-test as safely as possible. 1) Administer neuromuscular blocker and/or sedation to prevent patient coughing 2) Have ready, a metal

(1,650 × 1,275 (228 KB)) - 00:37, 17 May 2022

File:Abrams Chest Journal 2017 - Extracorporeal membrane oxygenation for adult resp failure.pdf (matches file content)

2017;195(9): 1253-1263. 24. Papazian L, Forel JM, Gacouin A, et al. Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med. 2010;363(12):1107-1116

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File:Drazen NEJM 2017 - Acute Respiratory Distress Syndrome.pdf (matches file content)

with moderate-to-severe ARDS is comparing neuromuscular blockade and deep sedation with no routine neuromuscular blockade and less sedation (NCT02509078)

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File:Schweickert - Chest - ICU-AW Review.pdf (matches file content)

adverse effects on strength. The association of neuromuscular weakness with prolonged use of neuromuscular blocking agents (NMBAs) has long been recognized and

(1,200 × 1,612 (251 KB)) - 00:39, 17 May 2022

File:Applied Physiology and COVID.pdf (matches file content)

require a higher PEEP, a lower tidal volume, prone positioning, neuromuscular blocking agents and, for the worst cases, VV-ECMO. Obviously, this second

(1,275 × 1,650 (332 KB)) - 00:30, 17 May 2022

File:Lancet2008-SAT Trial.pdf (matches file content)

escalating sedative doses due to ongoing agitation, were receiving neuromuscular blockers, had evidence of active myocardial ischaemia in the previous 24

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File:Goligher AJRCCM 2017 - Removing C02 for ARDS.pdf (matches file content)

J-M, Perez D, Seghboyan J-M, et al.; ACURASYS Study Investigators. Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med 2010;363:1107–1116

(1,275 × 1,650 (4.22 MB)) - 00:32, 17 May 2022

File:Goligher AJRCCM 2017 - Removing CO2 for ARDS.pdf (matches file content)

J-M, Perez D, Seghboyan J-M, et al.; ACURASYS Study Investigators. Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med 2010;363:1107–1116

(1,275 × 1,650 (3.11 MB)) - 00:33, 17 May 2022

File:CA1 Tutorial Book FINAL.pdf (matches file content)

cisatracurium) Neuromuscular Blocking Agents (NMBAs) • • Postoperative residual paralysis occurs frequently. Monitoring of neuromuscular blockade and pharmacological

(1,125 × 1,500 (7.21 MB)) - 11:03, 3 August 2021

Tonsillectomy and/or adenoidectomy
of the following: obesity, Down syndrome, craniofacial abnormalities, neuromuscular disorders, sickle cell disease, or mucopolysaccharidoses. Consider a

18 KB (1,618 words) - 13:19, 20 July 2022
Mediastinal tumor resection
Double lumen tube (left) vs bronchial blocker with SLT flexible bronchoscope for DLT placement vs bronchial blocker placement fluid warmer in case transfusion

10 KB (927 words) - 22:44, 10 December 2023

File:Zochios Chest 2017 - RV in ARDS.pdf (matches file content)

declared. References 6. Papazian L, Forel JM, Gacouin A, et al. Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med. 2010;363(12):

(1,200 × 1,612 (204 KB)) - 00:32, 17 May 2022

File:Rogers Contemporary Reviews in CC Medicine 2018 - Intra-abdominal hypertension.pdf (matches file content)

2015;47(1):54-62. 81. De Laet I, Hoste E, Verholen E, et al. The effect of neuromuscular blockers in patients with intra-abdominal hypertension. Intensive Care Med

(1,200 × 1,612 (1.29 MB)) - 00:42, 17 May 2022

File:January 2022.pdf (matches file content)

documented Train of Four (TOF) after the last dose of non-depolarizing neuromuscular blocker. All Faulty – departmental metric What is QSIC Working On? Last

(1,275 × 1,650 (1.05 MB)) - 11:23, 31 March 2023

File:Goligher 2016 Lancet - Guides to ventilation.pdf (matches file content)

Med 2015; 372: 747–55. Papazian L, Forel J-M, Gacouin A, et al. Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med 2010;

(1,240 × 1,665 (1.51 MB)) - 00:40, 17 May 2022

File:Wilcox Crit Care Med 2012 - Ed on NMB in emergent airways.pdf (matches file content)

Boston, MA REFERENCES 1. Wilcox SR, Bittner EA, Elmer J, et al: Neuromuscular blocking agent administration for emergent tracheal intubation is associated

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File:Anesthesia for Myocardial Revascularization.pdf (matches file content)

TECHNIQUES FOR CARDIAC SURGICAL PROCEDURES Neuromuscular Blocking Agents All of the available neuromuscular blocking agents have been used to produce adequate

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File:ARDS Vent Guidelines.pdf (matches file content)

J-M, Perez D, Seghboyan J-M, et al.; ACURASYS Study Investigators. Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med 2010;363:1107–1116

(1,218 × 1,631 (585 KB)) - 00:42, 17 May 2022

File:DelSorbo AnnalsATS 2017 - Guidelines for ARDS.pdf (matches file content)

JM, Perez D, Seghboyan JM, et al.; ACURASYS Study Investigators. Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med 2010;363:1107–1116

(1,218 × 1,631 (624 KB)) - 00:32, 17 May 2022

File:Fan JAMA 2018 - Review ARDS.pdf (matches file content)

Investigators. Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med. 2010;363(12):1107-1116. 80. Slutsky AS. Neuromuscular blocking

(1,275 × 1,650 (769 KB)) - 00:39, 17 May 2022

File:Multimodal analgesic therapy with gabapentin is associated with perioperative respiratory despression (Cavalcante 2017).pdf (matches file content)

anesthesia maintenance were isoflurane and desflurane. The effects of neuromuscular-blocking drugs were routinely monitored with nerve stimulator and reversed

(1,218 × 1,631 (104 KB)) - 00:35, 17 May 2022

Diaphragmatic plication
248–252. 1990-02-01. doi:10.1016/0003-4975(90)90146-W. ISSN 0003-4975. "Neuromuscular Disorders Affecting the Thorax: Diaphragm Paralysis". Pulmonology Advisor

11 KB (818 words) - 12:40, 5 April 2022

File:Pham Mayo Clinc Proc 2017 - Review of Mech Vent.pdf (matches file content)

Papazian L, Forel J-M, Gacouin A, et al; ACURASYS Study Investigators. Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med. 2010;363(12):1107-1116

(1,200 × 1,612 (653 KB)) - 00:33, 17 May 2022

File:Pham State of the Art.pdf (matches file content)

Papazian L, Forel J-M, Gacouin A, et al; ACURASYS Study Investigators. Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med. 2010;363(12):1107-1116

(1,200 × 1,612 (653 KB)) - 00:33, 17 May 2022

File:Bleaker - Perioperative Care of Patients Undergoing Major.3.pdf (matches file content)

TIVA without a neuromuscular blocking agent (Class IIb, Level of Evidence B-R). (2) To facilitate TIVA without a neuromuscular blocking agent, sufentanil

(1,218 × 1,631 (339 KB)) - 12:16, 25 August 2022

File:Del Sorbo ATS 2017 - Recommendations ards 2017.pdf (matches file content)

Lefrant JY, Guerin C, Prat G, Morange S, Roch A, Investigators AS. Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med 2010;363:1107-1116

(1,275 × 1,650 (551 KB)) - 00:41, 17 May 2022

File:Kacmarek 2016 CCM - OLA for ARDS.pdf (matches file content)

Patients were sedated to apnea before the recruitment maneuver and neuromuscular-blocking agents were used if necessary to insure patient safety during the

(1,218 × 1,631 (617 KB)) - 00:37, 17 May 2022

Mediastinoscopy
typically not indicated given small incision. Epidurals or peripheral nerve blocks may be placed post op if there is catastrophic conversion to median sternotomy

9 KB (755 words) - 16:53, 7 December 2023

File:Steadman ACNA Liver Transplants.pdf (matches file content)

sevoflurane administration [61]. Cisatracurium may be the preferred neuromuscular blocking agent in patients undergoing liver transplantation because of its

(900 × 1,350 (405 KB)) - 00:38, 17 May 2022

File:Perren Intensive Care Med 2013 - Managing Weaning Medical Ventilation.pdf (matches file content)

aminoglycosides, prolonged use of neuromuscular blocking agents) Neuromuscular transmission (MG, neuromuscular blocking agents) Critical illness myopathy

(1,240 × 1,647 (407 KB)) - 00:31, 17 May 2022

File:Perren Intensive Care Med 2013 - Ventilator weaning difficulties.pdf (matches file content)

aminoglycosides, prolonged use of neuromuscular blocking agents) Neuromuscular transmission (MG, neuromuscular blocking agents) Critical illness myopathy

(1,240 × 1,647 (407 KB)) - 00:33, 17 May 2022

File:Anesthetic management of traumatic brain injury.pdf (matches file content)

commonly performed in this group of patients. Succinylcholine, is the neuromuscular blocking agent of choice for this purpose. Minton, et al. found that after

(1,240 × 1,753 (1.21 MB)) - 00:30, 17 May 2022

File:Czosnyka 2017 Handbook of Clin Neurology - Increased ICP Management.pdf (matches file content)

normal (4.5–5.0 kPa; 34–38 mmHg) ● Sedation (propofol, fentanyl, neuromuscular blockers where required) ● Temperature: normothermia (36–37.5°C) If ICP >20

(1,133 × 1,547 (3.94 MB)) - 00:35, 17 May 2022

File:Kuo et al 2006 Lidocaine in Colonic Surgery.pdf (matches file content)

perioperative period were excluded. At the end of surgery, residual neuromuscular block was antagonized with edrophonium (0.8 mg kg 1) and atropine (0.01

(1,276 × 1,652 (104 KB)) - 00:41, 17 May 2022

MediaWiki:Gadget-calculator-drugs-data.js
neuromuscularBlockade: { name: 'Neuromuscular blockade', abbreviation: 'NMB' }, neuromuscularBlockadeReversal:

163 KB (11,506 words) - 13:34, 8 January 2023

File:Forman Stuart HMS CV 2015.pdf (matches file content)

goals can be extremely limited. 2014present Heartrate Response to Neuromuscular Block Reversal with Neostigmine Principal Investigator I initiated a data-mining

(1,275 × 1,650 (312 KB)) - 00:41, 17 May 2022

File:Antibiotic Selection in the ICU - Part 2.pdf (matches file content)

side effect is the augmentation of skeletal muscle paralysis when neuromuscular blocking drugs are used by inhibiting the release of acetylcholine and binding

(1,331 × 1,706 (352 KB)) - 00:32, 17 May 2022

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