Succinylcholine
From WikiAnesthesia
Succinylcholine
Trade names |
Anectine |
---|---|
Clinical data | |
Drug class |
Depolarizing neuromuscular blocker |
Uses |
Paralysis for intubation |
Contraindications |
History/risk of malignant hyperthermia |
Routes of administration |
Intravenous, intramuscular |
Dosage | |
Pharmacodynamics | |
Mechanism of action |
Depolarizing blockade of neuromuscular junction |
Adverse effects |
Bradycardia, hyperkalemia, malignant hyperthermia, myalgias |
Pharmacokinetics | |
Onset of action |
30-60 seconds (IV) |
Duration of action |
5-10 minutes (IV) |
Metabolism |
Plasma cholinesterase |
Physical and chemical data | |
Article quality | |
Editor rating | |
User likes | 0 |
Succinylcholine, also known as suxamethonium, is a short-acting neuromuscular blocker used during intubation.
Uses
Contraindications
Absolute contraindications
- hyperkalemia
- increased risk of malignant hyperthermia
- open globe injury
- allergy
Precautions
Pharmacology
Pharmacodynamics
Mechanism of action
Adverse effects
Pharmacokinetics
Chemistry and formulation
History
References
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