Opioids

List of common opioids

Receptors

μ1 - euphoria

μ2 - hypoventilation, constipation, dependent

δ - hypoventilation, constipation, dependent

κ - antagonize many of the μ effects and engenders diuresis

σ - dysphoria

Opium alkaloids and semisynthetic derivatives

Opium alkaloids

• Codeine
• Morphine

Semisynthetic derivatives

• Buprenorphine (partial agonist)
• Hydrocodone
• Hydromorphone
• Naloxone (antagonist)
• Naltrexone (antagonist)
• Oxycodone

Synthetic opioids

• Alfentanil
• Fentanyl
• Meperidine
• Methadone
• Remifentanil
• Sufentanil
• Piritramide

Molecular structure

• Molecular structure of opium alkaloids
• 

  Codeine

• 

  Morphine

• Molecular structure of semisynthetic derivatives
• 

  Hydrocodone

• 

  Hydromorphone

• 

  Oxycodone

• 

  Naloxone (antagonist)

• 

  Naltrexone (antagonist)

• 

  Buprenorphine (partial agonist)

• Molecular structure of anilidopiperidine opioids
• 

  Alfentanil

• 

  Fentanyl

• 

  Remifentanil

• 

  Sufentanil

• Molecular structure of other synthetic opioids
• 

  Meperidine

• 

  Methadone