Difference between revisions of "Opioids"
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==List of common opioids== | ==List of common opioids== | ||
===Receptors=== | |||
μ1 - euphoria | |||
μ2 - hypoventilation, constipation, dependent | |||
δ - hypoventilation, constipation, dependent | |||
κ - antagonize many of the μ effects and engenders diuresis | |||
σ - dysphoria | |||
===Opium alkaloids and semisynthetic derivatives=== | ===Opium alkaloids and semisynthetic derivatives=== | ||
====Opium alkaloids==== | |||
*[[Codeine]] | *[[Codeine]] | ||
*[[Codeine|Morphine]] | |||
====Semisynthetic derivatives==== | |||
*[[Buprenorphine]] (partial agonist) | |||
*[[Hydrocodone]] | *[[Hydrocodone]] | ||
*[[Hydromorphone]] | *[[Hydromorphone]] | ||
*[[Naloxone]] (antagonist) | *[[Naloxone]] (antagonist) | ||
*[[Naltrexone]] (antagonist) | *[[Naltrexone]] (antagonist) | ||
*[[Oxycodone]] | *[[Oxycodone]] | ||
===Synthetic opioids=== | |||
*[[Alfentanil]] | |||
*[[Fentanyl]] | |||
*[[Meperidine]] | |||
*[[Methadone]] | |||
*[[Remifentanil]] | |||
*[[Sufentanil]] | |||
*[[Piritramide]] | |||
==Molecular structure== | |||
<gallery widths="150px" heights="150px" perrow="4" caption="Molecular structure of opium alkaloids"> | <gallery widths="150px" heights="150px" perrow="4" caption="Molecular structure of opium alkaloids"> | ||
File:Codeine.svg|[[Codeine]] | File:Codeine.svg|[[Codeine]] | ||
| Line 16: | Line 43: | ||
File:Hydrocodone.svg|[[Hydrocodone]] | File:Hydrocodone.svg|[[Hydrocodone]] | ||
File:Hydromorphone.svg|[[Hydromorphone]] | File:Hydromorphone.svg|[[Hydromorphone]] | ||
File:Oxycodone.svg|[[Oxycodone]] | |||
File:Naloxone.svg|[[Naloxone]] (antagonist) | File:Naloxone.svg|[[Naloxone]] (antagonist) | ||
File:Naltrexone.svg|[[Naltrexone]] (antagonist) | File:Naltrexone.svg|[[Naltrexone]] (antagonist) | ||
File: | File:Buprenorphine.svg|[[Buprenorphine]] (partial agonist) | ||
</gallery> | </gallery> | ||
<gallery widths="150px" heights="150px" perrow="4" caption="Molecular structure of anilidopiperidine opioids"> | <gallery widths="150px" heights="150px" perrow="4" caption="Molecular structure of anilidopiperidine opioids"> | ||
File:Alfentanil.svg|[[Alfentanil]] | File:Alfentanil.svg|[[Alfentanil]] | ||
| Line 33: | Line 54: | ||
File:Sufentanil.svg|[[Sufentanil]] | File:Sufentanil.svg|[[Sufentanil]] | ||
</gallery> | </gallery> | ||
<gallery widths="150px" heights=" | <gallery widths="150px" heights="150px" perrow="4" caption="Molecular structure of other synthetic opioids"> | ||
File:Meperidine.svg|[[Meperidine]] | File:Meperidine.svg|[[Meperidine]] | ||
File:Methadone.svg|[[Methadone]] | File:Methadone.svg|[[Methadone]] | ||
</gallery> | </gallery> | ||
Latest revision as of 09:16, 29 January 2023
List of common opioids
Receptors
μ1 - euphoria
μ2 - hypoventilation, constipation, dependent
δ - hypoventilation, constipation, dependent
κ - antagonize many of the μ effects and engenders diuresis
σ - dysphoria
Opium alkaloids and semisynthetic derivatives
Opium alkaloids
Semisynthetic derivatives
- Buprenorphine (partial agonist)
- Hydrocodone
- Hydromorphone
- Naloxone (antagonist)
- Naltrexone (antagonist)
- Oxycodone
Synthetic opioids
Molecular structure
- Molecular structure of opium alkaloids
- Molecular structure of semisynthetic derivatives
Naloxone (antagonist)
Naltrexone (antagonist)
Buprenorphine (partial agonist)
- Molecular structure of anilidopiperidine opioids
- Molecular structure of other synthetic opioids
