Difference between revisions of "Opioids"
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==List of common opioids== | ==List of common opioids== | ||
===Receptors=== | |||
μ1 - euphoria | |||
μ2 - hypoventilation, constipation, dependent | |||
δ - hypoventilation, constipation, dependent | |||
κ - antagonize many of the μ effects and engenders diuresis | |||
σ - dysphoria | |||
===Opium alkaloids and semisynthetic derivatives=== | ===Opium alkaloids and semisynthetic derivatives=== | ||
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*[[Remifentanil]] | *[[Remifentanil]] | ||
*[[Sufentanil]] | *[[Sufentanil]] | ||
*[[Piritramide]] | |||
==Molecular structure== | ==Molecular structure== | ||
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File:Hydrocodone.svg|[[Hydrocodone]] | File:Hydrocodone.svg|[[Hydrocodone]] | ||
File:Hydromorphone.svg|[[Hydromorphone]] | File:Hydromorphone.svg|[[Hydromorphone]] | ||
File:Oxycodone.svg|[[Oxycodone]] | |||
File:Naloxone.svg|[[Naloxone]] (antagonist) | File:Naloxone.svg|[[Naloxone]] (antagonist) | ||
File:Naltrexone.svg|[[Naltrexone]] (antagonist) | File:Naltrexone.svg|[[Naltrexone]] (antagonist) | ||
File: | File:Buprenorphine.svg|[[Buprenorphine]] (partial agonist) | ||
</gallery> | </gallery> | ||
<gallery widths="150px" heights="150px" perrow="4" caption="Molecular structure of anilidopiperidine opioids"> | <gallery widths="150px" heights="150px" perrow="4" caption="Molecular structure of anilidopiperidine opioids"> |
Latest revision as of 08:16, 29 January 2023
List of common opioids
Receptors
μ1 - euphoria
μ2 - hypoventilation, constipation, dependent
δ - hypoventilation, constipation, dependent
κ - antagonize many of the μ effects and engenders diuresis
σ - dysphoria
Opium alkaloids and semisynthetic derivatives
Opium alkaloids
Semisynthetic derivatives
- Buprenorphine (partial agonist)
- Hydrocodone
- Hydromorphone
- Naloxone (antagonist)
- Naltrexone (antagonist)
- Oxycodone
Synthetic opioids
Molecular structure
Naloxone (antagonist)
Naltrexone (antagonist)
Buprenorphine (partial agonist)