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==== Adverse effects<!-- Describe any potential adverse effects of the drug. --> ====
==== Adverse effects<!-- Describe any potential adverse effects of the drug. --> ====
Protamine Reactions:
* Type 1: Hypotension from rapid administration (histamine release mediated)
* Type 2:
** a: True anaphylactic reaction (IgE mediated)
** b: Immediate anaphylactoid reaction
** c: Delayed anaphylactoid reaction
* Type 3: Catastrophic pulmonary vasoconstriction (IgG/complement mediated)


=== Pharmacokinetics<!-- Describe the pharmacokinetics of the drug. --> ===
=== Pharmacokinetics<!-- Describe the pharmacokinetics of the drug. --> ===

Latest revision as of 10:49, 10 November 2021

Protamine
Clinical data
Pharmacodynamics
Pharmacokinetics
Physical and chemical data
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Provide a brief summary of this drug here.

Uses

Contraindications

Absolute contraindications

Precautions

Pharmacology

Pharmacodynamics

Mechanism of action

Adverse effects

Protamine Reactions:

  • Type 1: Hypotension from rapid administration (histamine release mediated)
  • Type 2:
    • a: True anaphylactic reaction (IgE mediated)
    • b: Immediate anaphylactoid reaction
    • c: Delayed anaphylactoid reaction
  • Type 3: Catastrophic pulmonary vasoconstriction (IgG/complement mediated)

Pharmacokinetics

Chemistry and formulation

History

References