Protamine
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Protamine
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Provide a brief summary of this drug here.
Uses
Contraindications
Absolute contraindications
Precautions
Pharmacology
Pharmacodynamics
Mechanism of action
Adverse effects
Protamine Reactions:
- Type 1: Hypotension from rapid administration (histamine release mediated)
- Type 2:
- a: True anaphylactic reaction (IgE mediated)
- b: Immediate anaphylactoid reaction
- c: Delayed anaphylactoid reaction
- Type 3: Catastrophic pulmonary vasoconstriction (IgG/complement mediated)