Glycopyrrolate

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Glycopyrrolate
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Glycopyrrolate is an anticholinergic drug commonly used in anesthesia to treat bradycardia and decrease secretions. It notably does not cross the blood-brain barrier and consequently has very few central effects.

Uses

  • Treat reflex bradycardia due to vasovagal reactions
  • Reduce secretions (salivary, tracheobronchial, pharyngeal)
  • Use in conjunction with neostigmine to prevent neostigmine's muscarinic effects such as bradycardia in neuromuscular blocking reversal

Contraindications

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Pharmacology

Pharmacodynamics

Mechanism of action

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