Glycopyrrolate
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Glycopyrrolate is an anticholinergic drug commonly used in anesthesia to treat bradycardia and decrease secretions. It notably does not cross the blood-brain barrier and consequently has very few central effects.

Uses

  • Treat reflex bradycardia due to vasovagal reactions
  • Reduce secretions (salivary, tracheobronchial, pharyngeal)
  • Use in conjunction with neostigmine to prevent neostigmine's muscarinic effects such as bradycardia in neuromuscular blocking reversal

Contraindications

Absolute contraindications

Precautions

Pharmacology

Pharmacodynamics

Mechanism of action

Adverse effects

Pharmacokinetics

Chemistry and formulation

History

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