|Signs and symptoms||Hypertension
|Diagnosis||Urine metanephrines and catecholamines Abdominal CT/MRI for localization|
|Treatment||Surgical resection Alpha/beta blockade|
Pheochromocytoma is a rare neuroendocrine disease of the adrenal gland where catecholamine-secreting tumors cause hypertension. Pheochromocytoma is present in 0.05% - 0.2% of hypertensive individuals, the incidence of the disease presents equally between men and women with a distribution across age groups but peaks in between 40 and 50 years of age. The classic presentation of the disease is a triad of symptoms including headache, palpitations, diaphoresis with a documented clinical sign of hypertension (present in 90% of patients with pheochromocytoma). However, patients can often present with less definitive symptoms such as tremor, anxiety, flushing, weight loss, and hyperglycemia. While the majority of pheochromocytoma emerges from adrenal tumors, roughly 15-20% can be extra-adrenal in etiology.
Related surgical procedures
Signs and symptoms
- Lo, Chung-Yau; Lam, King-Yin; Wat, Ming-Sun; Lam, Karen S. (2000-03-01). "Adrenal pheochromocytoma remains a frequently overlooked diagnosis". The American Journal of Surgery. 179 (3): 212–215. doi:10.1016/S0002-9610(00)00296-8. ISSN 0002-9610. PMID 10827323.
- Yeh, Michael; Livhits, Masha; Duh, Quan-Yang (2022). "The Adrenal Glands". Sabiston textbook of surgery : the biological basis of modern surgical practice. Courtney M., Jr. Townsend, R. Daniel Beauchamp, B. Mark Evers, Kenneth L. Mattox, David C. Sabiston (21st ed.). St. Louis, Missour. ISBN 978-0-323-64064-0. OCLC 1235959889.
- Peramunage, Dasun; Nikravan, Sara (2020-03-01). "Anesthesia for Endocrine Emergencies". Anesthesiology Clinics. 38 (1): 149–163. doi:10.1016/j.anclin.2019.10.006. ISSN 1932-2275. PMID 32008649.