Mannitol

Mannitol

Clinical data
Drug class	Osmotic diuretic
Uses	Reduction of intracranial pressure, Treatment of cerebral edema
Routes of administration	Intravenous
Dosage
Pharmacodynamics
Mechanism of action	Osmotic diuresis
Pharmacokinetics
Physical and chemical data
Article quality
Editor rating	In development
User likes	0

Mannitol is an osmotic diuretic that is often used to reduce cerebral edema and therefore reduce intracranial pressure.

Uses

• Reduction of intracranial pressure
• Treatment of cerebral edema
• Diuresis during kidney transplant

Contraindications

• Anuric renal failure
• Severe pulmonary edema

Pharmacology

Pharmacodynamics

Adverse effects

• Pulmonary edema in patients with heart failure or renal failure
• Hypernatremia from volume depletion
• Hyperkalemia
• Metabolic acidosis
• Acute Kidney Injury