Mannitol

Mannitol

Clinical data
Drug class	Osmotic diuretic
Uses	Reduction of intracranial pressure, Treatment of cerebral edema
Routes of administration	Intravenous
Dosage
Mannitol 0.25-1 g/kg IV Weight kglbg Height cmminft Age yrmowk SexFM Indication  Indication: Reduction of intracranial pressure Route  Route: Intravenous
Pharmacodynamics
Mechanism of action	Osmotic diuresis
Pharmacokinetics
Physical and chemical data
Article quality
Editor rating	In development
User likes	0

Mannitol is an osmotic diuretic that is often used to reduce cerebral edema and therefore reduce intracranial pressure.

Uses

• Reduction of intracranial pressure
• Treatment of cerebral edema
• Diuresis during kidney transplant

Contraindications

• Anuric renal failure
• Severe pulmonary edema

Pharmacology

Pharmacodynamics

Adverse effects

• Pulmonary edema in patients with heart failure or renal failure
• Hypernatremia from volume depletion
• Hyperkalemia
• Metabolic acidosis
• Acute Kidney Injury