Benzocaine
Clinical data
Pharmacodynamics
Pharmacokinetics
Physical and chemical data
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Benzocaine is an ester local anesthetic commonly used topically or in cough drops.

Uses

It is available in oral preparations (lozenges, throat spray), topical preparations (commonly for oral ulcers) or otic preparations.

Contraindications

Absolute contraindications

Precautions

Pharmacology

Pharmacodynamics

Mechanism of action

Adverse effects

  • Risk of methemoglobinemia

Pharmacokinetics

  • Metabolized by esters
  • pKa 3.5

Chemistry and formulation

  • Ester local anesthetic
  • Formed from ethanol and PABA

History

References