Succinylcholine

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Succinylcholine
Trade names Anectine
Succinylcholine.svg
Clinical data
Drug class Depolarizing neuromuscular blocker
Uses Paralysis for intubation
Contraindications History/risk of malignant hyperthermia
Conditions which proliferate extrajunctional acetylcholine receptors
Routes of administration Intravenous, intramuscular
Dosage 0.5-1.5 mg/kg
Pharmacodynamics
Mechanism of action Depolarizing blockade of neuromuscular junction
Adverse effects Bradycardia, hyperkalemia, malignant hyperthermia, myalgias
Pharmacokinetics
Onset of action 30-60 seconds (IV)
2-3 minutes (IM)
Duration of action 5-10 minutes (IV)
10-30 minutes (IM)
Metabolism Plasma cholinesterase
Physical and chemical data


Succinylcholine, also known as suxamethonium, is a short-acting neuromuscular blocker used during intubation.

Uses

Contraindications

Absolute contraindications

Precautions

Pharmacology

Pharmacodynamics

Mechanism of action

Adverse effects

Pharmacokinetics

Chemistry and formulation

History

References