Difference between revisions of "Pheochromocytoma"
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{{Infobox comorbidity | {{Infobox comorbidity | ||
| other_names = | | other_names = | ||
| anesthetic_relevance = | | anesthetic_relevance = Critical | ||
| specialty = | | specialty = Endocrinology | ||
| signs_symptoms = | | signs_symptoms = Hypertension | ||
| diagnosis = | Headache | ||
| treatment = | Diaphoresis | ||
Tachycardia | |||
| diagnosis = Urine metanephrines and catecholamines | |||
Abdominal CT/MRI for localization | |||
| treatment = Surgical resection | |||
Alpha/beta blockade | |||
| image = | | image = | ||
| caption = | | caption = | ||
}} | }} | ||
'''Pheochromocytoma''' is a rare neuroendocrine disease of the adrenal gland where catecholamine-secreting tumors cause hypertension. Pheochromocytoma is present in 0.05%<ref>{{Cite journal|last=Lo|first=Chung-Yau|last2=Lam|first2=King-Yin|last3=Wat|first3=Ming-Sun|last4=Lam|first4=Karen S.|date=2000-03-01|title=Adrenal pheochromocytoma remains a frequently overlooked diagnosis|url=https://www.americanjournalofsurgery.com/article/S0002-9610(00)00296-8/abstract|journal=The American Journal of Surgery|language=English|volume=179|issue=3|pages=212–215|doi=10.1016/S0002-9610(00)00296-8|issn=0002-9610|pmid=10827323}}</ref> - 0.2%<ref>{{Cite book|last=Yeh|first=Michael|url=https://www.worldcat.org/oclc/1235959889|title=Sabiston textbook of surgery : the biological basis of modern surgical practice|last2=Livhits|first2=Masha|last3=Duh|first3=Quan-Yang|date=2022|publisher=|others=Courtney M., Jr. Townsend, R. Daniel Beauchamp, B. Mark Evers, Kenneth L. Mattox, David C. Sabiston|year=|isbn=978-0-323-64064-0|edition=21st|location=St. Louis, Missour|pages=|chapter=The Adrenal Glands|oclc=1235959889}}</ref> of hypertensive individuals, the incidence of the disease presents equally between men and women with a distribution across age groups but peaks in between 40 and 50 years of age. The classic presentation of the disease is a triad of symptoms including headache, palpitations, diaphoresis with a documented clinical sign of hypertension (present in 90% of patients with pheochromocytoma)<ref>{{Cite journal|last=Peramunage|first=Dasun|last2=Nikravan|first2=Sara|date=2020-03-01|title=Anesthesia for Endocrine Emergencies|url=https://www.anesthesiology.theclinics.com/article/S1932-2275(19)30088-6/abstract|journal=Anesthesiology Clinics|language=English|volume=38|issue=1|pages=149–163|doi=10.1016/j.anclin.2019.10.006|issn=1932-2275|pmid=32008649}}</ref>. However, patients can often present with less definitive symptoms such as tremor, anxiety, flushing, weight loss, and hyperglycemia. While the majority of pheochromocytoma emerges from adrenal tumors, roughly 15-20% can be extra-adrenal in etiology. | |||
== Anesthetic implications<!-- Briefly summarize the anesthetic implications of this comorbidity. --> == | == Anesthetic implications<!-- Briefly summarize the anesthetic implications of this comorbidity. --> == | ||
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== References == | == References == | ||
<references /> | |||
[[Category:Comorbidities]] | [[Category:Comorbidities]] | ||
Revision as of 01:53, 9 June 2021
| Anesthetic relevance |
Critical |
|---|---|
| Anesthetic management |
{{{anesthetic_management}}} |
| Specialty |
Endocrinology |
| Signs and symptoms |
Hypertension Headache Diaphoresis Tachycardia |
| Diagnosis |
Urine metanephrines and catecholamines Abdominal CT/MRI for localization |
| Treatment |
Surgical resection Alpha/beta blockade |
| Article quality | |
| Editor rating | |
| User likes | 0 |
Pheochromocytoma is a rare neuroendocrine disease of the adrenal gland where catecholamine-secreting tumors cause hypertension. Pheochromocytoma is present in 0.05%[1] - 0.2%[2] of hypertensive individuals, the incidence of the disease presents equally between men and women with a distribution across age groups but peaks in between 40 and 50 years of age. The classic presentation of the disease is a triad of symptoms including headache, palpitations, diaphoresis with a documented clinical sign of hypertension (present in 90% of patients with pheochromocytoma)[3]. However, patients can often present with less definitive symptoms such as tremor, anxiety, flushing, weight loss, and hyperglycemia. While the majority of pheochromocytoma emerges from adrenal tumors, roughly 15-20% can be extra-adrenal in etiology.
Anesthetic implications
Preoperative optimization
Intraoperative management
Postoperative management
Related surgical procedures
Pathophysiology
Signs and symptoms
Diagnosis
Treatment
Medication
Surgery
Prognosis
Epidemiology
References
- ↑ Lo, Chung-Yau; Lam, King-Yin; Wat, Ming-Sun; Lam, Karen S. (2000-03-01). "Adrenal pheochromocytoma remains a frequently overlooked diagnosis". The American Journal of Surgery. 179 (3): 212–215. doi:10.1016/S0002-9610(00)00296-8. ISSN 0002-9610. PMID 10827323.
- ↑ Yeh, Michael; Livhits, Masha; Duh, Quan-Yang (2022). "The Adrenal Glands". Sabiston textbook of surgery : the biological basis of modern surgical practice. Courtney M., Jr. Townsend, R. Daniel Beauchamp, B. Mark Evers, Kenneth L. Mattox, David C. Sabiston (21st ed.). St. Louis, Missour. ISBN 978-0-323-64064-0. OCLC 1235959889.
- ↑ Peramunage, Dasun; Nikravan, Sara (2020-03-01). "Anesthesia for Endocrine Emergencies". Anesthesiology Clinics. 38 (1): 149–163. doi:10.1016/j.anclin.2019.10.006. ISSN 1932-2275. PMID 32008649.
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