Maximum dosage of local anesthetics

From WikiAnesthesia
Revision as of 20:51, 23 May 2022 by Tony Wang (talk | contribs) (Created page)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)

Local anesthetics must be dosed appropriately to prevent local anesthetic systemic toxicity (LAST)

Local anesthetic Without epinephrine With epinephrine
Bupivacaine* 2.5 mg/kg 3 mg/kg
Lidocaine 5 mg/kg 7 mg/kg
Ropivacaine 3 mg/kg --

* An easy way to remember bupivacaine (aka plain Marcaine) is to know that the patient's body weight is equivalent to the volume (in mL) of bupivacaine 0.25% that can be given. For example, for a 70kg patient, 70 mL of bupivacaine 0.25% is the maximum allowable dose.