(Added information on on the uses and adverse effects of mannitol. Changed formatting.)
 
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* Reduction of intracranial pressure
* Reduction of intracranial pressure
* Treatment of cerebral edema
* Treatment of cerebral edema
*Diuresis during kidney transplant


== Contraindications<!-- List contraindications and precautions for use of the drug. -->==
== Contraindications<!-- List contraindications and precautions for use of the drug. -->==
Anuric renal failure, severe pulmonary edema
 
* Anuric renal failure
* Severe pulmonary edema


===Absolute contraindications<!-- List absolute contraindications for use of the drug. If none, this section may be removed. -->===
===Absolute contraindications<!-- List absolute contraindications for use of the drug. If none, this section may be removed. -->===
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====Adverse effects<!-- Describe any potential adverse effects of the drug. --><!-- List precautions for use of the drug. If none, this section may be removed. -->====
====Adverse effects<!-- Describe any potential adverse effects of the drug. --><!-- List precautions for use of the drug. If none, this section may be removed. -->====
Pulmonary edema in patients with heart failure or renal failure, hypernatremia from volume depletion, hyperkalemia, metabolic acidosis, and AKI
 
* Pulmonary edema in patients with heart failure or renal failure
* Hypernatremia from volume depletion
* Hyperkalemia
* Metabolic acidosis
* Acute Kidney Injury


===Pharmacokinetics<!-- Describe the pharmacokinetics of the drug. -->===
===Pharmacokinetics<!-- Describe the pharmacokinetics of the drug. -->===

Latest revision as of 16:10, 11 July 2022

Mannitol
Clinical data
Drug class

Osmotic diuretic

Uses

Reduction of intracranial pressure, Treatment of cerebral edema

Routes of administration

Intravenous

Dosage
Pharmacodynamics
Mechanism of action

Osmotic diuresis

Pharmacokinetics
Physical and chemical data
Article quality
Editor rating
In development
User likes
0

Mannitol is an osmotic diuretic that is often used to reduce cerebral edema and therefore reduce intracranial pressure.

Uses

  • Reduction of intracranial pressure
  • Treatment of cerebral edema
  • Diuresis during kidney transplant

Contraindications

  • Anuric renal failure
  • Severe pulmonary edema

Absolute contraindications

Precautions

Pharmacology

Pharmacodynamics

Mechanism of action

Adverse effects

  • Pulmonary edema in patients with heart failure or renal failure
  • Hypernatremia from volume depletion
  • Hyperkalemia
  • Metabolic acidosis
  • Acute Kidney Injury

Pharmacokinetics

Chemistry and formulation

History

References