Amniotic fluid embolism

Amniotic fluid embolism

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An amniotic fluid embolism (AFE) is a rare but serious condition with high morbidity and mortality. It is characterized by cardiopulmonary collapse and disseminated intravascular coagulation (DIC). It is the second-leading cause of peripartum maternal death in the US and number one cause of peripartum cardiac arrest.

Risk Factors

Risk factors for the development of AFE are advanced maternal age, multiparity, male fetuses, and trauma.

Pathophysiology

AFE is poorly understood.