Naloxone
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Revision as of 23:17, 29 March 2022 by Chris Rishel (talk | contribs) (Added embedded dosage calculation)
Naloxone
| Trade names |
Narcan |
|---|---|
 | |
| Clinical data | |
| Uses |
Reversal of opioid agonism |
| Routes of administration |
Intramuscular, Intranasal, Intravenous |
| Dosage | |
| Pharmacodynamics | |
| Mechanism of action |
μ-opioid antagonism |
| Adverse effects |
Acute opioid withdrawal, hypotension, arrhythmias, pulmonary edema |
| Pharmacokinetics | |
| Onset of action |
1-2 minutes (IV) |
| Duration of action |
30-60 minutes |
| Metabolism |
Hepatic |
| Elimination half-life |
1-1.5 hours |
| Physical and chemical data | |
| Formula |
C19H21NO4 |
| Molar mass |
327.380 g/mol |
| Article quality | |
| Editor rating | |
| User likes | 0 |
Naloxone is an opioid-receptor antagonist which is used for the reversal of opioid overdose.
Uses
Contraindications
Absolute contraindications
Precautions
Pharmacology
Pharmacodynamics
Mechanism of action
Adverse effects
Pharmacokinetics
Chemistry and formulation
History
References
Top contributors: Chris Rishel