Tranexamic acid
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Revision as of 17:20, 10 August 2021 by Chris Rishel (talk | contribs) (Created page with "{{Infobox drug reference | trade_names = Lysteda, Cyklokapron | drug_class = Antifibrinolytic | drug_class_color = | uses = Reduction of blood loss | contraindications = | r...")
Tranexamic acid
| Trade names |
Lysteda, Cyklokapron |
|---|---|
| Clinical data | |
| Drug class |
Antifibrinolytic |
| Uses |
Reduction of blood loss |
| Routes of administration |
Intravenous |
| Pharmacodynamics | |
| Pharmacokinetics | |
| Physical and chemical data | |
| Article quality | |
| Editor rating | |
| User likes | 0 |
Tranexamic acid (TXA) is an antifibrinolytic drug used to prevent or treat blood loss from surgery and trauma.
Uses
Contraindications
Absolute contraindications
- Hypersensitivity to TXA
- Coronary or vascular stent placed within the past 6 months (may be extended to one year if appropriate)
- DVT, PE, MI or ischemic stroke within the past 6 months (may be extended to one year if appropriate)
- Subarachnoid hemorrhage
- Retinal vein or artery occlusion
- Active intravascular clotting
- Concomitant use of clotting factor concentrates or anti-inhibitor coagulant concentrates
- History of seizure disorder, or elevated seizure risk
Precautions
- Bleeding disorders or hypercoagulable state/disorders
- Reduce dose in renal insufficiency (see package insert for recommendations)
Pharmacology
Pharmacodynamics
Mechanism of action
Adverse effects
Pharmacokinetics
Chemistry and formulation
History
References
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