Mannitol
| Clinical data | |
| Drug class |
Osmotic diuretic |
|---|---|
| Uses |
Reduction of intracranial pressure, Treatment of cerebral edema |
| Routes of administration |
Intravenous |
| Dosage | |
| Pharmacodynamics | |
| Mechanism of action |
Osmotic diuresis |
| Pharmacokinetics | |
| Physical and chemical data | |
| Article quality | |
| Editor rating | |
| User likes | 0 |
Mannitol is an osmotic diuretic that is often used to reduce cerebral edema and therefore reduce intracranial pressure.
Uses
- Reduction of intracranial pressure
- Treatment of cerebral edema
- Diuresis during kidney transplant
Contraindications
- Anuric renal failure
- Severe pulmonary edema
Absolute contraindications
Precautions
Pharmacology
Pharmacodynamics
Mechanism of action
Adverse effects
- Pulmonary edema in patients with heart failure or renal failure
- Hypernatremia from volume depletion
- Hyperkalemia
- Metabolic acidosis
- Acute Kidney Injury
Pharmacokinetics
Chemistry and formulation
History
References
Top contributors: Chris Rishel and Scott Alan Blaine