Ketamine

Ketamine is a dissociative anesthetic agent used for induction and maintenance of general anesthesia, sedation, and analgesia.

Ketamine stimulates sympathetic tone and typically increases heart rate, blood pressure, and cardiac output.

Uses, Dosing, & Administration

Give the drug's indications and the doses for each indication. When the drug can be given my mutltiple routes be sure to specify the route of administration. When dosing is by weight be sure to specify total, adjusted, or ideal body weight.

When there are a range of doses it can be helpful to describe how the dose is chosen and/or give a 'typical' dose. When doses are repeated or a drug is given by infusion it can be helpful to describe titration intervals and increments.

Indication:

• Route/Administration Dose Unit (weight qualifier) timing

Induction of anesthesia:

• IV over 30 to 60 seconds 0.5 to 2 mg/kg (LBW)
  • 0.5 to 1 mg/kg in patients with shock
• IM 4 to 6 mg/kg

Maintenance of anesthesia (adjunct to TIVA or inhalational anesthesia)

• 0.25 to 0.35 mg/kg at incision, followed by continuous infusion up to 1 mg/kg/hour

Further Resources

You can use this section to provide sources that offer further information that may be of interest to users. Present them as a bulleted list and give a brief description of the resource.