Succinylcholine

Succinylcholine

Trade names	Anectine
Clinical data
Drug class	Depolarizing neuromuscular blocker
Uses	Paralysis for intubation
Contraindications	History/risk of malignant hyperthermia Conditions which proliferate extrajunctional acetylcholine receptors
Routes of administration	Intravenous, intramuscular
Dosage	0.5-1.5 mg/kg
Pharmacodynamics
Mechanism of action	Depolarizing blockade of neuromuscular junction
Adverse effects	Bradycardia, hyperkalemia, malignant hyperthermia, myalgias
Pharmacokinetics
Onset of action	30-60 seconds (IV) 2-3 minutes (IM)
Duration of action	5-10 minutes (IV) 10-30 minutes (IM)
Metabolism	Plasma cholinesterase
Physical and chemical data
Article quality
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Succinylcholine, also known as suxamethonium, is a short-acting neuromuscular blocker used during intubation.