Ketamine
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Revision as of 04:23, 12 November 2021 by Chris Rishel (talk | contribs)
Ketamine
Trade names |
Ketalar |
---|---|
Clinical data | |
Drug class |
Sedative hypnotic |
Uses |
Induction and maintenance of anesthesia, sedation, analgesia |
Contraindications |
|
Routes of administration |
IV, IM, IN, PO, PR |
Dosage |
Induction of anesthesia:
Subdissociative analgesia:
|
Pharmacodynamics | |
Mechanism of action |
NMDA antagonism |
Adverse effects |
Laryngospasm Hypersalivation Emesis Emergence reaction |
Pharmacokinetics | |
Onset of action |
|
Duration of action |
|
Metabolism |
Liver (CYP3A4, CYP2B6) |
Elimination half-life |
2.5-3 hours |
Protein binding |
23-47% |
Physical and chemical data | |
Formula |
C13H16ClNO |
Molar mass |
237.73 g/mol |
Article quality | |
Editor rating | |
User likes | 0 |
Ketamine is a dissociative anesthetic used for the induction of anesthesia, procedural sedation, and as an analgesic adjunct.