(Added information on on the uses and adverse effects of mannitol. Changed formatting.)
 
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* Reduction of intracranial pressure
* Reduction of intracranial pressure
* Treatment of cerebral edema
* Treatment of cerebral edema
*Diuresis during kidney transplant


== Contraindications<!-- List contraindications and precautions for use of the drug. -->==
== Contraindications<!-- List contraindications and precautions for use of the drug. -->==
Anuric renal failure, severe pulmonary edema
 
* Anuric renal failure
* Severe pulmonary edema


===Absolute contraindications<!-- List absolute contraindications for use of the drug. If none, this section may be removed. -->===
===Absolute contraindications<!-- List absolute contraindications for use of the drug. If none, this section may be removed. -->===
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====Adverse effects<!-- Describe any potential adverse effects of the drug. --><!-- List precautions for use of the drug. If none, this section may be removed. -->====
====Adverse effects<!-- Describe any potential adverse effects of the drug. --><!-- List precautions for use of the drug. If none, this section may be removed. -->====
Pulmonary edema in patients with heart failure or renal failure, hypernatremia from volume depletion, hyperkalemia, metabolic acidosis, and AKI
 
* Pulmonary edema in patients with heart failure or renal failure
* Hypernatremia from volume depletion
* Hyperkalemia
* Metabolic acidosis
* Acute Kidney Injury


===Pharmacokinetics<!-- Describe the pharmacokinetics of the drug. -->===
===Pharmacokinetics<!-- Describe the pharmacokinetics of the drug. -->===

Latest revision as of 16:10, 11 July 2022

Mannitol
Clinical data
Drug class

Osmotic diuretic

Uses

Reduction of intracranial pressure, Treatment of cerebral edema

Routes of administration

Intravenous

Dosage
  • 0.25-1 g/kg IV
Indication 
Reduction of intracranial pressure
Route 
Intravenous
Pharmacodynamics
Mechanism of action

Osmotic diuresis

Pharmacokinetics
Physical and chemical data
Article quality
Editor rating
In development
User likes
0

Mannitol is an osmotic diuretic that is often used to reduce cerebral edema and therefore reduce intracranial pressure.

Uses

  • Reduction of intracranial pressure
  • Treatment of cerebral edema
  • Diuresis during kidney transplant

Contraindications

  • Anuric renal failure
  • Severe pulmonary edema

Absolute contraindications

Precautions

Pharmacology

Pharmacodynamics

Mechanism of action

Adverse effects

  • Pulmonary edema in patients with heart failure or renal failure
  • Hypernatremia from volume depletion
  • Hyperkalemia
  • Metabolic acidosis
  • Acute Kidney Injury

Pharmacokinetics

Chemistry and formulation

History

References