(Created page with "{{Infobox drug reference | trade_names = | drug_class = | drug_class_color = | uses = | contraindications = | routes = | dosage = }} Provide a brief summary of this dr...")
 
m (Added embedded dosage calculation)
 
Line 7: Line 7:
| routes =  
| routes =  
| dosage =  
| dosage =  
| dosage_calculation = hydrocortisone
}}
}}



Latest revision as of 01:11, 30 March 2022

Hydrocortisone
Clinical data
Dosage
  • Minor procedures
    • Take usual AM steroid dose, no supplementation required
  • Moderate surgical stress
    • Take usual AM steroid dose
    • 50 mg before incision
    • 25 mg q8h for 24h
  • Major surgical stress
    • Take usual AM steroid dose
    • 100 mg before incision
    • 50 mg q8h for 24h
    • Taper dose by 50% per day until at usual dose

Indication 
HPA axis suppression
Route 
Intravenous

  • HPA axis suppression is unlikely in patients taking less than 5 mg/day of prednisone or equivalent
    • Methylprednisolone 4 mg/day, dexamethasone 0.5 mg/day, hydrocortisone 20 mg/day
  • HPA axis suppression is likely in patients taking more than 20 mg/day of prednisone or equivalent
    • Methylprednisolone 16 mg/day, dexamethasone 2 mg/day, hydrocortisone 80 mg/day
  • Patients taking intermediate doses or who have discontinued higher doses in the previous year should undergo preoperative evaluation of their HPA axis

  1. Liu MM, Reidy AB, Saatee S, Collard CD. Perioperative Steroid Management: Approaches Based on Current Evidence. Anesthesiology. 2017 Jul;127(1):166-172. doi: 10.1097/ALN.0000000000001659. PMID: 28452806.
Pharmacodynamics
Pharmacokinetics
Physical and chemical data
Article quality
Editor rating
Unrated
User likes
0

Provide a brief summary of this drug here.

Uses

Contraindications

Absolute contraindications

Precautions

Pharmacology

Pharmacodynamics

Mechanism of action

Adverse effects

Pharmacokinetics

Chemistry and formulation

History

References