(Created page with "{{Infobox drug reference | trade_names = | drug_class =Osmotic diuretic | drug_class_color = | uses =Reduction of intracranial pressure, Treatment of cerebral edema | cont...")
 
 
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{{Infobox drug reference
{{Infobox drug reference
| trade_names =  
| trade_names =  
| drug_class =Osmotic diuretic  
| drug_class = Osmotic diuretic
| drug_class_color =  
| drug_class_color =  
| uses =Reduction of intracranial pressure, Treatment of cerebral edema  
| uses = Reduction of intracranial pressure, Treatment of cerebral edema
| contraindications =  
| contraindications =  
| routes =Intravenous  
| routes = Intravenous
| dosage =  
| dosage =  
|mechanism=Osmotic diuresis|adverse_effects=|time_onset=|duration=|metabolism=|halflife_redistribution=|halflife_elimination=|clearance=|protein_binding=}}
| dosage_calculation = mannitol
| mechanism = Osmotic diuresis
| adverse_effects =  
| time_onset =  
| duration =  
| metabolism =  
| halflife_redistribution =  
| halflife_elimination =  
| clearance =  
| protein_binding =  
}}


Provide a brief summary of this drug here.
'''Mannitol''' is an osmotic diuretic that is often used to reduce cerebral edema and therefore reduce intracranial pressure.  


==Uses<!-- Describe uses of the drug. If appropriate, add subsections for each indication. -->==
==Uses<!-- Describe uses of the drug. If appropriate, add subsections for each indication. -->==


==Contraindications<!-- List contraindications and precautions for use of the drug. -->==
* Reduction of intracranial pressure
* Treatment of cerebral edema
*Diuresis during kidney transplant
 
== Contraindications<!-- List contraindications and precautions for use of the drug. -->==
 
* Anuric renal failure
* Severe pulmonary edema


===Absolute contraindications<!-- List absolute contraindications for use of the drug. If none, this section may be removed. -->===
===Absolute contraindications<!-- List absolute contraindications for use of the drug. If none, this section may be removed. -->===


===Precautions<!-- List precautions for use of the drug. If none, this section may be removed. -->===
=== Precautions===


==Pharmacology==
==Pharmacology==
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====Mechanism of action<!-- Describe the mechanism of action for the primary uses of the drug. -->====
====Mechanism of action<!-- Describe the mechanism of action for the primary uses of the drug. -->====


====Adverse effects<!-- Describe any potential adverse effects of the drug. -->====
====Adverse effects<!-- Describe any potential adverse effects of the drug. --><!-- List precautions for use of the drug. If none, this section may be removed. -->====
 
* Pulmonary edema in patients with heart failure or renal failure
* Hypernatremia from volume depletion
* Hyperkalemia
* Metabolic acidosis
* Acute Kidney Injury


===Pharmacokinetics<!-- Describe the pharmacokinetics of the drug. -->===
===Pharmacokinetics<!-- Describe the pharmacokinetics of the drug. -->===

Latest revision as of 16:10, 11 July 2022

Mannitol
Clinical data
Drug class

Osmotic diuretic

Uses

Reduction of intracranial pressure, Treatment of cerebral edema

Routes of administration

Intravenous

Dosage
  • 0.25-1 g/kg IV
Indication 
Reduction of intracranial pressure
Route 
Intravenous
Pharmacodynamics
Mechanism of action

Osmotic diuresis

Pharmacokinetics
Physical and chemical data
Article quality
Editor rating
In development
User likes
0

Mannitol is an osmotic diuretic that is often used to reduce cerebral edema and therefore reduce intracranial pressure.

Uses

  • Reduction of intracranial pressure
  • Treatment of cerebral edema
  • Diuresis during kidney transplant

Contraindications

  • Anuric renal failure
  • Severe pulmonary edema

Absolute contraindications

Precautions

Pharmacology

Pharmacodynamics

Mechanism of action

Adverse effects

  • Pulmonary edema in patients with heart failure or renal failure
  • Hypernatremia from volume depletion
  • Hyperkalemia
  • Metabolic acidosis
  • Acute Kidney Injury

Pharmacokinetics

Chemistry and formulation

History

References