Maximum dosage of local anesthetics

Local anesthetics must be dosed appropriately to prevent local anesthetic systemic toxicity (LAST)

Local anesthetic	Without epinephrine	With epinephrine
Bupivacaine*	2.5 mg/kg	3 mg/kg
Lidocaine	5 mg/kg	7 mg/kg
Ropivacaine	3 mg/kg	--

* An easy way to remember bupivacaine (aka plain Marcaine) is to know that the patient's body weight is equivalent to the volume (in mL) of bupivacaine 0.25% that can be given. For example, for a 70kg patient, 70 mL of bupivacaine 0.25% is the maximum allowable dose.