Revision history of "Local anesthetic systemic toxicity"

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  • curprev 16:12, 12 September 2022Maura Dore talk contribs 12,841 bytes +11,238 Merged two similar pages about LAST
  • curprev 13:55, 15 March 2022Olivia Sutton talk contribs 1,603 bytes +1,603 Created page with " ====== Local Anesthetic Systemic Toxicity (LAST) ====== * More vascular injection sites, dose, the local anesthetic's intrinsic pharmacokinetic properties, and the addition of a vasoactive agent all affect the risk for LAST * CNS toxicity: ** Local anesthetics readily cross the blood brain barrier ** Clinical manifestations: lightheadedness, tinnitus, tongue numbness, metallic taste → CNS excitation (block inhibitory pathways) → CNS depression, seizure → coma * C..." Tag: Visual edit