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  • File:Opioids and Cancer Recurrence Review (Cata 2016).pdf
    Brief review of opioids and cancer recurrence
    (1,275 × 1,650 (779 KB)) - 00:30, 17 May 2022
  • File:NMCP Anesthesiology Introductory Guide (rotator manual) Booklet Print.pdf (matches file content)
    Synthetic µ‐opioid agonist Synthetic µ‐opioid agonist µ‐opioid agonist NMDA receptor antagonist NSAID Selective cyclooxygenase inhibitor Direct α2 agonist Weak
    (1,650 × 1,275 (2.25 MB)) - 07:31, 29 August 2023
  • File:NMCP Anesthesiology Introductory Guide (rotator manual).pdf (matches file content)
    Synthetic µ-opioid agonist Synthetic µ-opioid agonist µ-opioid agonist NMDA receptor antagonist NSAID Selective cyclooxygenase inhibitor Direct α2 agonist Weak
    (825 × 1,275 (1.49 MB)) - 07:39, 29 August 2023
  • File:The future of nonoperating room anesthesia in the 21st century emphasis on quality and safety.pdf (matches file content)
    produces significant analgesia with less tolerance. Kappa opioid agonists is another group of opioid analogs under development that show promise in providing
    (1,222 × 1,629 (545 KB)) - 00:38, 17 May 2022
  • File:Acute Pain Syllabus 2.2019.pdf (matches file content)
    morpine. (Partial opioid agonists- buprenorphine/ nalbuphine used to treat opioid SEs such as pruritis may precipitate abrupt opioid withdrawal in this
    (1,275 × 1,650 (2.06 MB)) - 15:41, 21 April 2021
  • File:WHO Guidelines for Cancer Pain.pdf (matches file content)
    taking a single opioid, what is the evidence for the practice of opioid rotation or opioid switching as compared with continuing use of one opioid in order to
    (1,062 × 1,476 (1.04 MB)) - 13:39, 20 March 2023
  • File:Bingel et al 2011 Remifentanil Placebo Nocebo.pdf (matches file content)
    being on an opioid is not due to opioid tolerance. This was confirmed by control experiment II (fig. S5), in which we demonstrated that the opioid regimen
    (1,237 × 1,575 (1.67 MB)) - 00:38, 17 May 2022
  • File:Opioid (remifentanil) induced hyperalgesia review and meta-analysis (Fletcher 2014).pdf (matches file content)
    pain; postoperative, analgesics opioid, analgesics opioid; remifentanil, pain Accepted for publication: 22 January 2014 Opioid-induced hyperalgesia (OIH) has
    (1,275 × 1,647 (421 KB)) - 00:32, 17 May 2022
  • File:Brown MMGA A&A 11 19.pdf (matches file content)
    EE Special Article Figure 2. Opioids. The mechanisms of opioid-induced antinociception are produced by opioid binding to opioid receptors in the brainstem
    (1,218 × 1,631 (844 KB)) - 00:35, 17 May 2022
  • File:Anesthesia for Myocardial Revascularization.pdf (matches file content)
    to a reduction in systemic vascular resistance. 13 Opioids These drugs are pure opioid agonists and none provides complete ­ anesthesia as ­defined by
    (900 × 1,350 (775 KB)) - 00:30, 17 May 2022
  • File:CA1 Tutorial Book FINAL.pdf (matches file content)
    min ITE tip: mixed opioid agonists and antagonists » Mu opioid agonist and kappa receptor antagonist » Buprenorphine » Mu agonist and nmda antagonist
    (1,125 × 1,500 (7.21 MB)) - 11:03, 3 August 2021
  • File:Inflammatory Masses Associated with Intrathecal Drug Infusion.pdf (matches file content)
    Under other experimental conditions, an opioid-induced increase in lymphocyte activity may involve �–opioid receptors [33]. However, the in vivo role
    (1,237 × 1,631 (355 KB)) - 15:22, 7 March 2024
  • File:CA1 - Pharmacology.pdf (matches file content)
    and physiology of nociception • Opioids (mechanisms and side effects) • Non-opioid analgesics o NSAIDs o Alpha-2 agonists o NMDA antagonists o Gabapentinoids
    (1,275 × 1,650 (268 KB)) - 00:37, 17 May 2022
  • File:Anesthesia for Bronchoscopy.pdf (matches file content)
    both agonists and reverse agonists to the GABA-A receptor. Slight activity, which resembles a reverse agonist at low concentrations and an agonist at high
    (975 × 1,455 (139 KB)) - 00:33, 17 May 2022
  • File:Rauck - Long-Term Intrathecal Opioid Therapy with a Patient-Activated, Implated Delivery System.pdf
    Rauck, Richard L., et al. "Long-term intrathecal opioid therapy with a patient-activated, implanted delivery system for the treatment of refractory cancer
    (1,237 × 1,650 (255 KB)) - 13:46, 20 March 2023
  • File:CA1 - Pharmacology 2020.pdf (matches file content)
    and physiology of nociception • Opioids (mechanisms and side effects) • Non-opioid analgesics o NSAIDs o Alpha-2 agonists o NMDA antagonists o Gabapentinoids
    (1,275 × 1,650 (258 KB)) - 00:35, 17 May 2022
  • File:Retrospective study in endoscopy - JClinAn - Silveira.pdf (matches file content)
    biomarker of GLP-1 agonists responsiveness and for determination of suitability for prolonged treatment [1]. Semaglutide, a GLP-1 agonist with a half-life
    (1,240 × 1,653 (936 KB)) - 13:05, 15 June 2023
  • File:Basic pharmacological principals final.pdf (matches file content)
    Pharmacodynamics • Full agonists (oxycodone, methadone, hydrocodone, morphine) – Activate receptor to the maximum capacity • Partial agonists (buprenorphine)
    (2,000 × 1,125 (2.22 MB)) - 00:40, 17 May 2022
  • File:Ketamine Consensus Guidelines for Acute Pain 2018.pdf (matches file content)
    whether they were opioid tolerant. Opioid-naive patients were administered ketamine infusions of 0.05 to 0.4 mg/kg per hour, opioid-tolerant patients received
    (1,162 × 1,612 (225 KB)) - 00:35, 17 May 2022
  • File:Polyanalgesic Consensus Conference 2012 Guidelines for Intrathecal Medication Delivery Systems.pdf (matches file content)
    5 Morphine + bupivacaine Ziconotide + opioid Opioid (morphine, hydromorphone, or fentanyl) + clonidine Opioid + clonidine + bupivacaine Sufentanil + bupivacaine
    (1,237 × 1,631 (636 KB)) - 15:39, 7 March 2024
  • File:Bleaker - Perioperative Care of Patients Undergoing Major.3.pdf (matches file content)
    effectively reduce postoperative opioid requirements,94 especially in the opioid-naive patients.95 Recommendation: (1) To reduce opioid consumption in the immediate
    (1,218 × 1,631 (339 KB)) - 12:16, 25 August 2022
  • File:Howard - Chronic Pelvic Pain.pdf (matches file content)
    illegal substances are not good candidates for opioid treatment may diminish cases of iatrogenic addiction. Opioid maintenance therapy for chronic pelvic pain
    (1,200 × 1,612 (267 KB)) - 13:34, 20 March 2023
  • File:Smith 2009 Mechanisms of Acetaminophen.pdf (matches file content)
    APAP include opioid-like and serotonergic (31,32), with the latter (28) of much more significance (16). Although the involvement of μ-opioid receptors in
    (1,275 × 1,650 (308 KB)) - 00:40, 17 May 2022
  • File:Consensus Guidelines for PONV A&A Jan 2014.pdf (matches file content)
    with opioid-free regional anesthesia26 and reduced opioid consumption through the use of non-opioid analgesics,27 perioperative alpha-2 agonists,28 and
    (1,218 × 1,631 (904 KB)) - 00:40, 17 May 2022
  • File:Bittner 2014 Periop Anes Management of Burn Patient.pdf (matches file content)
    during 2 Hz nerve stimulation.64,104 Opioids Opioid requirements are increased in burn-injured patients. Opioid tolerance makes pain management challenging
    (1,218 × 1,631 (985 KB)) - 00:34, 17 May 2022
  • File:Benedetti 1996 Naloxone and Placebo Analgesia.pdf (matches file content)
    hypothesize that /~, 6 and K opioid receptors resulted to be involved. Therefore, the present results can not differentiate which opioid peptides play a role in
    (1,275 × 1,687 (774 KB)) - 00:34, 17 May 2022
  • File:Maldonado Crit Care Clin 2017 - Alcohol Withdrawal Syndrome Algorithms.pdf (matches file content)
    effects of alpha-2 agonists. Meanwhile the alpha-2B subtype is found predominantly in the thalamus183 and predominantly mediates alpha-2 agonists’ sedative actions
    (900 × 1,350 (1.37 MB)) - 00:34, 17 May 2022
  • File:Ruscic Penile Transplantation Anesthesia Analgesia 2017.pdf (matches file content)
    surgery.5 Continuous regional analgesia provides superior analgesia over opioid-based analgesic techniques and vasodilation from sympathetic blockade, a
    (1,218 × 1,631 (95 KB)) - 00:33, 17 May 2022
  • File:Common Peds Cases PDF.pdf (matches file content)
    heart will not respond normally to indirect acting catecholamines. Direct agonists (isoproterenol, epinephrine) preferred. Postoperative  Most patients that
    (1,240 × 1,753 (777 KB)) - 11:00, 7 October 2021
  • File:Retrospective Endo - Stark Ann Pharmacotx 2022.pdf (matches file content)
    gastric emptying (alpha-2 adrenergic agonists, tricyclic antidepressants, opioids, calcium channel blockers, dopamine agonists, cholinergic antagonists, octreotide
    (1,256 × 1,631 (276 KB)) - 13:08, 15 June 2023
  • File:Obstetric Anesthesia CA1 Lecture 05Feb21.pdf (matches file content)
    Duration Morphine Opioid 2-4 mg IV 3-4 h Hydromorphone Opioid 0.5-2 mg IV 1-2 h Meperidine Opioid 25-50 mg IV 2-3 h Fentanyl Opioid 25-50 mcg IV
    (1,500 × 843 (1.41 MB)) - 00:35, 17 May 2022
  • File:Maher Neuromodulation- Technology at the Neural Interface 2017.pdf (matches file content)
    association between higher opioid doses and greater odds of a 50% reduction in opioid use may be the reflective of SCS’s ability to reduce opioid reliance in chronic
    (1,237 × 1,631 (175 KB)) - 00:36, 17 May 2022
  • File:Maher et al-2017-Neuromodulation- Technology at the Neural Interface.pdf (matches file content)
    association between higher opioid doses and greater odds of a 50% reduction in opioid use may be the reflective of SCS’s ability to reduce opioid reliance in chronic
    (1,237 × 1,631 (175 KB)) - 00:30, 17 May 2022
  • File:Chang 2020 Muscle Relaxants for Pain.pdf (matches file content)
    depression that are particularly seen in concomitant use of alcohol, anxiolytics, opioid, or other sedatives.11 One hypothesis regarding patient-reported pain relief
    (900 × 1,350 (308 KB)) - 00:36, 17 May 2022
  • File:Doleman et al 2015 Preventive Acetaminophen Review and Meta-Analysis.pdf (matches file content)
    Therefore, alternative strategies to reduce opioid consumption have been proposed, such as the use of non– opioid-based multimodal analgesia.3 Acetaminophen
    (1,162 × 1,612 (603 KB)) - 00:38, 17 May 2022
  • File:Nguyen 2007 CCM - Synergism erythro and reglan.pdf (matches file content)
    Response. After we controlled for treatment effects, only sedation with opioid and/or benzodiazepines (relative risk, 3.30, conCrit Care Med 2007 Vol.
    (1,218 × 1,631 (563 KB)) - 00:37, 17 May 2022
  • File:Hawkins NEJM 2010.pdf (matches file content)
    combined with an opioid for this purpose. The quality of the analgesia is improved with the combined use of a local anesthetic and an opioid as compared with
    (1,181 × 1,575 (950 KB)) - 00:39, 17 May 2022
  • File:ANES Intraoperative Methadone in Surgical Patients.pdf (matches file content)
    Total Intraoperative Intraoperative Intravenous Opioid Used Opioid Used in the Control in the Control Opioid Used Total Postoperatively Group Group Methadone
    (1,218 × 1,631 (641 KB)) - 00:32, 17 May 2022
  • File:Polyanalgesic Consensus Conference—2012 IDDS Trial Recommendations.pdf (matches file content)
    systemic opioid use, systemic opioid use at the final follow-up visit in the Anderson et al. (4) study was 57% lower for all patients, and systemic opioid use
    (1,237 × 1,631 (425 KB)) - 15:39, 7 March 2024
  • File:FY23 Roadmap 7.22.pdf (matches file content)
    multiple illicit substances (i.e. polysubstance abuse) Opioid naïve patients at risk of developing opioid dependence postoperatively 33 © 2016 by the Johns
    (1,275 × 1,650 (1.35 MB)) - 19:23, 26 August 2022
  • File:Solt Ken HMS CV 2014.pdf (matches file content)
    PMID: 23268668. Letters to the editor 1. Brown EN, Solt K. Management of opioid analgesic overdose. N Engl J Med 2012;367(14):1370-1. PMID: 23034040. 2
    (1,275 × 1,650 (164 KB)) - 00:40, 17 May 2022
  • File:Obstetric Anesthesia Review for the Basic Boards 08May18.pdf (matches file content)
    hypokalemia Calcium Channel Blockers - Nifedipine - CCBs superior to Beta-agonists for long term reduction of preterm labor and improving neonatal outcomes
    (1,500 × 843 (1.23 MB)) - 00:33, 17 May 2022
  • File:Anesthesia for GI.pdf (matches file content)
    benzodiazepine/opioid sedation.1 The median satisfaction score for propofol was 10 on a scale where 10 was defined as best, while benzodiazepine and opioid in combination
    (1,240 × 1,753 (1.38 MB)) - 00:34, 17 May 2022
  • File:Forman Stuart HMS CV 2015.pdf (matches file content)
    208B06A1B9&View={5DE6F758-9E31-481F-A249-64F550386EB2} 16. Forman SA. Epidural Opioid Pharmacokinetics and Analgesia Mechanisms. Microcourse including handout
    (1,275 × 1,650 (312 KB)) - 00:41, 17 May 2022
  • File:Russell, Treatment of obstetric post-dural puncture headache.pdf (matches file content)
    analgesia should be offered to women with postnatal headache. Opioid analgesia Stronger opioid medication such as morphine or oxycodone is often given to
    (1,240 × 1,653 (321 KB)) - 00:32, 17 May 2022
  • File:IVF anesthesia.pdf (matches file content)
    started. The opioid is usually the first agent given because the goal of sedation is pain management during oocyte retrieval. The opioid most frequently
    (1,240 × 1,753 (655 KB)) - 00:35, 17 May 2022
  • File:Deiner AMA 2017 - Intraop dexmedetomidine not prevent delirium.pdf (matches file content)
    The α2-adrenergic agonist dexmedetomidine has a range of effects that may be beneficial in the postoperative period, including opioid-sparing properties
    (1,275 × 1,650 (271 KB)) - 00:35, 17 May 2022
  • File:Reade AMA 2016 - dex for delirium.pdf (matches file content)
    the study, or (6) there was a known contraindication to haloperidol or α2-agonists. Patients were randomized, stratified by site and age (<55 years and ≥55
    (1,275 × 1,650 (337 KB)) - 00:33, 17 May 2022
  • File:Anderson CJA 2014.pdf (matches file content)
    the patient may direct administration of opioids and benzodiazepines titrated to patient comfort. Often an opioid and benzodiazepine are titrated with a
    (1,240 × 1,647 (433 KB)) - 00:35, 17 May 2022
  • File:Anesthetic management of traumatic brain injury.pdf (matches file content)
    sufentanil, and remifentanil are commonly used in TBI patients. Careful opioid titration should be observed to avoid hypotension secondary to a reduction
    (1,240 × 1,753 (1.21 MB)) - 00:30, 17 May 2022

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