Barbiturates
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Barbiturates
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Provide a brief summary of this drug here.
Uses
Contraindications
Absolute contraindications
Acute intermittent porphyria: Barbiturates stimulate synthesis of aminolevulinic acid synthetase, which is the rate limiting enzyme in the formation of porphyrin. In AIP, defective porphobilinogen deaminase causes buildup of porphobilinogen.
Precautions
Pharmacology
Pharmacodynamics
Mechanism of action
Barbiturates are GABA agonists.
Adverse effects
Pharmacokinetics
Chemistry and formulation
History
References
Top contributors: Tony Wang and George Tye