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{{Infobox drug reference
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Provide a brief summary of this drug here.
== Uses<!-- Describe uses of the drug. If appropriate, add subsections for each indication. --> ==
== Contraindications<!-- List contraindications and precautions for use of the drug. --> ==
=== Absolute contraindications<!-- List absolute contraindications for use of the drug. If none, this section may be removed. --> ===
Acute intermittent porphyria: Barbiturates stimulate synthesis of ''aminolevulinic acid synthetase'', which is the rate limiting enzyme in the formation of porphyrin. In AIP, defective ''porphobilinogen'' ''deaminase'' causes buildup of porphobilinogen.
=== Precautions<!-- List precautions for use of the drug. If none, this section may be removed. --> ===
== Pharmacology ==
=== Pharmacodynamics<!-- Describe the effects of the drug on the body. If appropriate, add subsections by organ system --> ===
==== Mechanism of action<!-- Describe the mechanism of action for the primary uses of the drug. --> ====
Barbiturates are GABA agonists.
Barbiturates are GABA agonists.


== Contraindications ==
==== Adverse effects<!-- Describe any potential adverse effects of the drug. --> ====
 
=== Pharmacokinetics<!-- Describe the pharmacokinetics of the drug. --> ===
 
== Chemistry and formulation<!-- Describe the chemistry and formulation of the drug. --> ==
 
== History<!-- Describe the historical development of the drug. --> ==


=== Acute intermittent porphyria ===
== References ==
Barbiturates stimulate synthesis of ''aminolevulinic acid synthetase'', which is the rate limiting enzyme in the formation of porphyrin.


In AIP, defective ''porphobilinogen'' ''deaminase'' causes buildup of porphobilinogen.
[[Category:Drug reference]]

Latest revision as of 10:10, 13 November 2023

Barbiturates
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Provide a brief summary of this drug here.

Uses

Contraindications

Absolute contraindications

Acute intermittent porphyria: Barbiturates stimulate synthesis of aminolevulinic acid synthetase, which is the rate limiting enzyme in the formation of porphyrin. In AIP, defective porphobilinogen deaminase causes buildup of porphobilinogen.

Precautions

Pharmacology

Pharmacodynamics

Mechanism of action

Barbiturates are GABA agonists.

Adverse effects

Pharmacokinetics

Chemistry and formulation

History

References