MRI-guided transurethral ultrasound ablation

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MRI-guided transurethral ultrasound ablation
Anesthesia type

General

Airway

ETT

Lines and access

PIV

Monitors

Standard ASA

Primary anesthetic considerations
Preoperative
Intraoperative

Paralysis to maintain akinesis for image guidance

Postoperative
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MRI-guided Transurethral Ultrasound Ablation (TULSA) is a minimally invasive, incision-free procedure used to treat prostate cancer and enlarged prostate (BPH). It uses high-frequency sound waves to generate heat and destroy targeted prostate tissue from the "inside out."

The procedure is commonly referred to by its commercial name, TULSA-PRO.

Overview

Indications

  • Prostate cancer
  • BPH

Surgical procedure

  • The Device: A thin, rod-shaped device is inserted into the urethra while the patient is under GA.
  • MRI Guidance: The entire procedure takes place inside an MRI scanner. This allows the surgeon to see the prostate in high-definition and map out exactly which tissue needs to be destroyed and which should be saved.
  • The Ablation: The device emits directional ultrasound waves that heat the prostate tissue to about 55°C–60°C (131°F–140°F), which kills the cancerous or excess cells.
  • Real-Time Cooling: While the ultrasound heats the prostate, the device circulates cool water to protect the walls of the urethra and the rectum.
  • Precision Monitoring: The MRI provides real-time "heat maps," allowing the doctor to adjust the intensity and direction of the ultrasound every few seconds to ensure the heat stays within the treatment boundary.

Preoperative management

Patient evaluation

System Considerations
Airway
Neurologic
Cardiovascular
Pulmonary
Gastrointestinal
Hematologic
Renal
Endocrine
Other

Labs and studies

Operating room setup

Patient preparation and premedication

Regional and neuraxial techniques

Intraoperative management

Monitoring and access

Induction and airway management

Positioning

Maintenance and surgical considerations

Maintain paralysis for MRI image guidance precision. Consider rocuronium/vecuronium infusion.

Emergence

Postoperative management

Disposition

Pain management

Potential complications

Procedure variants

Variant 1 Variant 2
Unique considerations
Indications
Position
Surgical time
EBL
Postoperative disposition
Pain management
Potential complications

References