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• 10:08, 13 November 2023 George Tye talk contribs created page Barbiturates (Created page with "Barbiturates are GABA agonists. == Contraindications == === Acute intermittent porphyria === Barbiturates stimulate synthesis of ''aminolevulinic acid synthetase'', which is the rate limiting enzyme in the formation of porphyrin. In AIP, defective ''porphobilinogen'' ''deaminase'' causes buildup of porphobilinogen.")