Nitroprusside

Nitroprusside

Trade names	Nipride, Nitropress
Clinical data
Drug class	Nitrovasodilator
Routes of administration	Intravenous
Dosage
Nitroprusside Adult dosing Bolus 12.5-25 mcg IV 0.025-0.05 mL of 500 mcg/mL Maintenance 0.3-2 mcg/kg/min IV More information about this dose Weight kglbg Height cmminft Age yrmowk SexFM Indication  Indication: Hypertension Route  Route: Intravenous Preparation  Preparation: 5 mcg/mL25 mcg/mL500 mcg/mL Titrate by 0.5 mcg/kg/min q3-5m until desired effect achieved High doses (8-10 mcg/kg/min) should not be used for more than 10 minutes Schulz V. Clinical pharmacokinetics of nitroprusside, cyanide, thiosulphate and thiocyanate. Clin Pharmacokinet. 1984 May-Jun;9(3):239-51. doi: 10.2165/00003088-198409030-00005. PMID: 6375932.
Pharmacodynamics
Mechanism of action	Nitric oxide production
Pharmacokinetics
Physical and chemical data
Article quality
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