Septal myectomy/myotomy
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Septal myectomy/myotomy
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Provide a brief summary here.
Overview
Myotomy and septal myectomy are surgical procedures used primarily to treat hypertrophic obstructive cardiomyopathy (HOCM). This condition is characterized by the thickening of the heart muscle, particularly the interventricular septum, which can obstruct blood flow.
Indications
- Hypertrophic obstructive cardiomyopathy (HOCM)
- Symptoms: dyspnea, palpitations, arrhythmia, syncope, heart failure, stroke, and sudden death
- Management of this condition can be medical, electrophysiological or surgical. This article will focus primarily on the open surgical technique[1]
- Symptomatic left ventricular outflow tract (LVOT) obstruction
- Severe mitral regurgitation due to systolic anterior motion (SAM) of the mitral valve
- Refractory symptoms despite medical management (e.g., dyspnea, syncope)
Surgical procedure
- TEE (transesophageal echocardiography) used intraoperatively to guide resection and assess results.
Preoperative management
Patient evaluation
| System | Considerations |
|---|---|
| Airway | Direct vs. indirect laryngoscopy |
| Neurologic | Paralysis, CPB |
| Cardiovascular | Biventricular function, valvular abnormalities, integrity of conduction and presence of arrhythmias |
| Pulmonary | |
| Gastrointestinal | |
| Hematologic | Coagulopathy, may be exacerbated by CPB |
| Renal | |
| Endocrine | |
| Other |
Labs and studies
- Cardiology Assessment: Detailed history and physical examination.
- Imaging: Echocardiogram to assess septal thickness and LVOT gradient. Cardiac MRI may also be used.
- Functional Testing: Stress testing to evaluate symptomatology and obstruction severity.
- Labs
- CBC
- CMP
- Coagulation studies
- Blood cultures
- +/- TEG if patient has history of comorbid condition that affects coagulopathy
Patient preparation and premedication
- Continued use of beta-blockers or calcium channel blockers until surgery.
- Consider anxiolytics like midazolam.
Intraoperative management
Monitoring and access
- Standard ASA monitors
- Arterial line
- Central access CVP +/- PA pressures(indicated for RV or LV failure)
- Transesophageal echo(TEE)
Induction and airway management
- General anesthesia with endotracheal intubation.
Positioning
- Supine position for surgical access.
- Shoulder roll
- Arms tucked
Maintenance and surgical considerations
- LV systolic function in patients with HOCM are usually normal to supranormal with a high ejection fraction.[2]
- Diastolic dysfunction in patients with HOCM is caused by decreased ventricular compliance and impaired ventricular relaxation.[1]
- Promote:
- Increased preload
- Trendelenburg positioning may be used for episodes of hypotension
- Adequate afterload
- Increased preload
- Avoid:
- Vasodilators
- Decreases in SVR
- Increased inotropy
- Increased chronotropy
- Can be treated in perioperative period with B-antagonists(ex. esmolol)[2]
- Outflow tract obstruction
*Interestingly, halothane has a good profile for patients with HOCM, given it decreases contractility and heart rate.
Emergence
Postoperative management
Disposition
- Intensive care unit (ICU) monitoring initially.
- Often intubated
- Frequently requiring pressors or inotropic agents post-CPB.
- Continuous ECG monitoring for arrhythmias.
Pain management
Potential complications
- Arrhythmias (atrial fibrillation, ventricular arrhythmias)
- Ventricular septal defect
- Mitral regurgitation
- Bleeding or pericardial effusion
- AV node block requiring pacemaker insertion
- CPB specific complications
Procedure variants
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References
- ↑ 1.0 1.1 Wigle, E. Douglas; Rakowski, Harry; Kimball, Brian P.; Williams, William G. (1995-10). "Hypertrophic Cardiomyopathy". Circulation. 92 (7): 1680–1692. doi:10.1161/01.CIR.92.7.1680. Check date values in:
|date=(help) - ↑ 2.0 2.1 Cregg, Nuala; Cheng, Davy C. H.; Karski, Jacek M.; Williams, William G.; Webb, Gary; Wigle, E. Douglas (1999-02-01). "Morbidity outcome in patients with hypertrophic obstructive cardiomyopathy undergoing cardiac septal myectomy: Early-extubation anesthesia versus high-dose opioid anesthesia technique". Journal of Cardiothoracic and Vascular Anesthesia. 13 (1): 47–52. doi:10.1016/S1053-0770(99)90173-8. ISSN 1053-0770.