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Trauma is a leading cause of death and disability worldwide, particularly in individuals under 45. Anesthetic management of trauma patients requires rapid decision-making, physiologic insight, and close coordination with surgical, emergency, and critical care teams. Hemorrhagic shock remains a primary driver of early mortality, with damage control resuscitation (DCR) principles serving as the cornerstone of early care (Fort & Zack-Guasp 2020).<ref>{{Cite journal|last=Fort|first=Alexander C.|last2=Zack-Guasp|first2=Richard A.|date=2020-03|title=Anesthesia for Patients with Extensive Trauma|url=https://pubmed.ncbi.nlm.nih.gov/32008648|journal=Anesthesiology Clinics|volume=38|issue=1|pages=135–148|doi=10.1016/j.anclin.2019.10.012|issn=1932-2275|pmid=32008648}}</ref> Anesthetic care begins in the trauma bay and extends through the operating room (OR) to the intensive care unit (ICU), requiring continuity and adaptability (Tobin et al. 2018).
Trauma is a leading cause of death and disability worldwide, particularly in individuals under 45. Anesthetic management of trauma patients requires rapid decision-making, physiologic insight, and close coordination with surgical, emergency, and critical care teams. Hemorrhagic shock remains a primary driver of early mortality, with damage control resuscitation (DCR) principles serving as the cornerstone of early care (Fort & Zack-Guasp 2020).<ref name=":0">{{Cite journal|last=Fort|first=Alexander C.|last2=Zack-Guasp|first2=Richard A.|date=2020-03|title=Anesthesia for Patients with Extensive Trauma|url=https://pubmed.ncbi.nlm.nih.gov/32008648|journal=Anesthesiology Clinics|volume=38|issue=1|pages=135–148|doi=10.1016/j.anclin.2019.10.012|issn=1932-2275|pmid=32008648}}</ref> Anesthetic care begins in the trauma bay and extends through the operating room (OR) to the intensive care unit (ICU), requiring continuity and adaptability (Tobin et al. 2018).<ref name=":1">{{Cite journal|last=Tobin|first=Joshua M.|last2=Barras|first2=William P.|last3=Bree|first3=Stephen|last4=Williams|first4=Necia|last5=McFarland|first5=Craig|last6=Park|first6=Claire|last7=Steinhiser|first7=David|last8=Stone|first8=R. Craig|last9=Stockinger|first9=Zsolt|date=2018-09-01|title=Anesthesia for Trauma Patients|url=https://pubmed.ncbi.nlm.nih.gov/30189066|journal=Military Medicine|volume=183|issue=suppl_2|pages=32–35|doi=10.1093/milmed/usy062|issn=1930-613X|pmid=30189066}}</ref>


== Overview ==
== Overview ==
Line 23: Line 23:
* Compartment syndrome
* Compartment syndrome


Indications for anesthetic involvement extend beyond the OR, often beginning with airway support, hemodynamic resuscitation, and pain management in the emergency department (Pollock et al. 2023).
Indications for anesthetic involvement extend beyond the OR, often beginning with airway support, hemodynamic resuscitation, and pain management in the emergency department (Pollock et al. 2023).<ref name=":2">{{Cite journal|last=Pollock|first=Gabriel A.|last2=Lo|first2=Jessie|last3=Chou|first3=Henry|last4=Kissen|first4=Michael S.|last5=Kim|first5=Michelle|last6=Zhang|first6=Vida|last7=Betz|first7=Alexander|last8=Perlman|first8=Ryan|date=2023-01|title=Advanced diagnostic and therapeutic techniques for anaesthetists in thoracic trauma: an evidence-based review|url=https://pubmed.ncbi.nlm.nih.gov/36096943|journal=British Journal of Anaesthesia|volume=130|issue=1|pages=e80–e91|doi=10.1016/j.bja.2022.07.005|issn=1471-6771|pmid=36096943}}</ref>


=== Surgical procedure ===
=== Surgical procedure ===
Trauma surgery encompasses a wide range of procedures, from exploratory laparotomy and thoracotomy to damage control orthopedics and vascular repair. Procedures are often staged, with initial operations focused on hemorrhage and contamination control, followed by definitive repair after physiologic stabilization (Tobin et al. 2018).
Trauma surgery encompasses a wide range of procedures, from exploratory laparotomy and thoracotomy to damage control orthopedics and vascular repair. Procedures are often staged, with initial operations focused on hemorrhage and contamination control, followed by definitive repair after physiologic stabilization (Tobin et al. 2018).<ref name=":1" />


== Preoperative management ==
== Preoperative management ==


=== Patient evaluation<!-- Describe the unique and important aspects of preoperative evaluation. Add or remove rows from the systems table as needed. --> ===
=== Patient evaluation<!-- Describe the unique and important aspects of preoperative evaluation. Add or remove rows from the systems table as needed. --> ===
Initial evaluation follows Advanced Trauma Life Support (ATLS) principles, with a primary survey (ABCDE) to identify and address life-threatening conditions (Fort & Zack-Guasp 2020).<ref>{{Cite journal|last=Fort|first=Alexander C.|last2=Zack-Guasp|first2=Richard A.|date=2020-03|title=Anesthesia for Patients with Extensive Trauma|url=https://pubmed.ncbi.nlm.nih.gov/32008648|journal=Anesthesiology Clinics|volume=38|issue=1|pages=135–148|doi=10.1016/j.anclin.2019.10.012|issn=1932-2275|pmid=32008648}}</ref> Neurologic status should be assessed with the Glasgow Coma Scale (GCS). Patients with traumatic brain injury, thoracic trauma, or unstable hemodynamics require special anesthetic consideration.
Initial evaluation follows Advanced Trauma Life Support (ATLS) principles, with a primary survey (ABCDE) to identify and address life-threatening conditions (Fort & Zack-Guasp 2020). <ref name=":0" />  
 
'''A – Airway with cervical spine protection'''
 
* Assess for patency: look for obstruction, facial trauma, or burns.
* Intervene with suction, airway adjuncts (e.g., oropharyngeal/nasopharyngeal airway), or definitive airway (endotracheal intubation) as needed.
* Always assume cervical spine injury in trauma patients; apply cervical collar and maintain manual in-line stabilization during airway maneuvers.
 
'''B – Breathing and ventilation'''
 
* Evaluate chest movement, symmetry, respiratory rate, and effort.
* Auscultate lung fields; identify pneumothorax, hemothorax, or flail chest.
* Provide oxygen; initiate positive pressure ventilation if inadequate.
* Consider needle decompression or chest tube for tension pneumothorax or massive hemothorax.
 
'''C – Circulation with hemorrhage control'''
 
* Check pulse rate, blood pressure, capillary refill, and skin perfusion.
* Look for external bleeding; apply direct pressure or tourniquets.
* Establish two large-bore IVs or intraosseous access.
* Initiate fluid resuscitation and activate massive transfusion protocol if needed.
* Perform FAST exam and pelvic X-ray for occult bleeding.
 
'''D – Disability (neurologic evaluation)'''
 
* Perform rapid neurologic assessment using the '''Glasgow Coma Scale (GCS)'''.
* Check pupillary size and response.
* Identify signs of traumatic brain injury or spinal cord injury.
 
'''E – Exposure and environmental control'''
 
* Fully expose the patient to identify hidden injuries.
* Prevent hypothermia using warm blankets, warming devices, and warmed IV fluids.
* Maintain privacy and dignity once life-threatening injuries are excluded.
 
Neurologic status should be assessed with the Glasgow Coma Scale (GCS). Patients with traumatic brain injury, thoracic trauma, or unstable hemodynamics require special anesthetic consideration.  
{| class="wikitable"
!'''Component'''
!'''Response'''
!'''Score'''
|-
|'''Eye Opening'''
|Spontaneous
|4
|-
|
|To voice
|3
|-
|
|To pain
|2
|-
|
|No response
|1
|-
|'''Verbal Response'''
|Oriented
|5
|-
|
|Confused
|4
|-
|
|Inappropriate words
|3
|-
|
|Incomprehensible sounds
|2
|-
|
|No response
|1
|-
|'''Motor Response'''
|Obeys commands
|6
|-
|
|Localizes pain
|5
|-
|
|Withdraws from pain
|4
|-
|
|Abnormal flexion (decorticate)
|3
|-
|
|Abnormal extension (decerebrate)
|2
|-
|
|No response
|1
|}
{| class="wikitable"
{| class="wikitable"
|+
|+
{| class="wikitable"
!'''System'''
!'''Considerations in Trauma and Anesthetic Implications'''
|-
|'''Airway'''
|Facial fractures, airway edema, blood/vomit, cervical spine instability; may require RSI or surgical airway
|-
|'''Neurologic'''
|Traumatic brain injury (TBI), spinal cord injury; avoid hypoxia/hypotension, maintain cerebral perfusion, use GCS
|-
|'''Cardiovascular'''
|Hemorrhagic shock, tamponade, myocardial contusion; requires volume resuscitation, blood products, vasoactive agents
|-
|'''Pulmonary'''
|Pneumothorax, hemothorax, pulmonary contusion, flail chest; manage with chest tubes, lung-protective ventilation
|-
|'''Gastrointestinal'''
|Bowel injury, hepatic/splenic laceration; risk of peritonitis, sepsis, rapid deterioration; damage control laparotomy may be needed
|-
|'''Hematologic'''
|Coagulopathy (trauma-induced or dilutional), massive transfusion; use balanced ratios, TXA, monitor with TEG/ROTEM
|-
|'''Renal'''
|Hypoperfusion, rhabdomyolysis, contrast-induced nephropathy; maintain perfusion, monitor creatinine, avoid nephrotoxins
|-
|'''Endocrine'''
|Adrenal insufficiency (especially in chronic steroid users), hyperglycemia; consider stress-dose steroids, tight glucose control
|-
|'''Other'''
|Hypothermia, acidosis, electrolyte disturbances (esp. hyperkalemia); actively warm patient, correct derangements, monitor closely
|}
!System
!System
!Considerations
!Considerations
Line 73: Line 204:
* Focused Assessment with Sonography for Trauma (FAST)
* Focused Assessment with Sonography for Trauma (FAST)
* Chest/pelvis radiographs
* Chest/pelvis radiographs
* Extended FAST (E-FAST) including lung and cardiac views (Pollock et al. 2023)
* Extended FAST (E-FAST) including lung and cardiac views (Pollock et al. 2023)<ref name=":2" />


Viscoelastic testing (e.g., TEG/ROTEM/QUANTRA) aids in goal-directed blood product administration during active resuscitation (Pollock et al. 2023).
Viscoelastic testing (e.g., TEG/ROTEM/QUANTRA) aids in goal-directed blood product administration during active resuscitation (Pollock et al. 2023).<ref name=":2" />


=== Operating room setup<!-- Describe any unique aspects of operating room preparation. Avoid excessively granular information. Use drug classes instead of specific drugs when appropriate. If none, this section may be removed. --> ===
=== Operating room setup<!-- Describe any unique aspects of operating room preparation. Avoid excessively granular information. Use drug classes instead of specific drugs when appropriate. If none, this section may be removed. --> ===


=== Patient preparation and premedication<!-- Describe any unique considerations for patient preparation and premedication. If none, this section may be removed. --> ===
=== Patient preparation and premedication<!-- Describe any unique considerations for patient preparation and premedication. If none, this section may be removed. --> ===
Premedication is often avoided in unstable trauma patients due to risk of hypotension and hypoventilation. Preoxygenation should be optimized; apneic oxygenation may be used if necessary (Tobin et al. 2018). Anticipate difficult airway and cervical spine precautions.
Premedication is often avoided in unstable trauma patients due to risk of hypotension and hypoventilation. Preoxygenation should be optimized; apneic oxygenation may be used if necessary (Tobin et al. 2018).<ref name=":1" /> Anticipate difficult airway and cervical spine precautions.


=== Regional and neuraxial techniques<!-- Describe any potential regional and/or neuraxial techniques which may be used for this case. If none, this section may be removed. --> ===
=== Regional and neuraxial techniques<!-- Describe any potential regional and/or neuraxial techniques which may be used for this case. If none, this section may be removed. --> ===
Regional anesthesia is increasingly used for trauma, particularly for extremity and rib fractures. Early blockade may improve pain control, decrease opioid exposure, and reduce the risk of chronic pain (Torrie 2022). However, coagulopathy, hypotension, and polytrauma may limit feasibility. Single-shot blocks are preferred in unstable patients (Torrie 2022).
Regional anesthesia is increasingly used for trauma, particularly for extremity and rib fractures. Early blockade may improve pain control, decrease opioid exposure, and reduce the risk of chronic pain (Torrie 2022).<ref name=":3">{{Cite journal|last=Torrie|first=Arissa M.|date=2022-10-01|title=Regional anesthesia and analgesia for trauma: an updated review|url=https://pubmed.ncbi.nlm.nih.gov/36044292|journal=Current Opinion in Anaesthesiology|volume=35|issue=5|pages=613–620|doi=10.1097/ACO.0000000000001172|issn=1473-6500|pmid=36044292}}</ref> However, coagulopathy, hypotension, and polytrauma may limit feasibility. Single-shot blocks are preferred in unstable patients (Torrie 2022).<ref name=":3" /><ref name=":4">{{Cite journal|last=Saranteas|first=Theodosios|last2=Koliantzaki|first2=Iosifina|last3=Savvidou|first3=Olga|last4=Tsoumpa|first4=Marina|last5=Eustathiou|first5=Georgia|last6=Kontogeorgakos|first6=Vasileios|last7=Souvatzoglou|first7=Rizos|date=2019-07|title=Acute pain management in trauma: anatomy, ultrasound-guided peripheral nerve blocks and special considerations|url=https://pubmed.ncbi.nlm.nih.gov/30735016|journal=Minerva Anestesiologica|volume=85|issue=7|pages=763–773|doi=10.23736/S0375-9393.19.13145-8|issn=1827-1596|pmid=30735016}}</ref>


== Intraoperative management ==
== Intraoperative management ==
Line 94: Line 225:
* Central venous access if volume resuscitation is ongoing
* Central venous access if volume resuscitation is ongoing
* Temperature monitoring
* Temperature monitoring
* POCUS or TEE for hemodynamic assessment (Pollock et al. 2023)
* POCUS or TEE for hemodynamic assessment (Pollock et al. 2023)<ref name=":2" />


=== Induction and airway management<!-- Describe the important considerations and general approach to the induction of anesthesia and how the airway is typically managed for this case. --> ===
=== Induction and airway management<!-- Describe the important considerations and general approach to the induction of anesthesia and how the airway is typically managed for this case. --> ===
Rapid sequence induction (RSI) is standard in trauma to mitigate aspiration risk.  
Rapid sequence induction (RSI) is standard in trauma to mitigate aspiration risk.  


Ketamine and etomidate are commonly used induction agents due to hemodynamic stability; propofol is often avoided in hypovolemic patients (Pillay & Hardcastle 2016). RSI with succinylcholine or rocuronium are used for neuromuscular blockade.
Ketamine and etomidate are commonly used induction agents due to hemodynamic stability; propofol is often avoided in hypovolemic patients (Pillay & Hardcastle 2016).<ref>{{Cite journal|last=Pillay|first=Leressè|last2=Hardcastle|first2=Timothy|date=2017-05|title=Collective Review of the Status of Rapid Sequence Intubation Drugs of Choice in Trauma in Low- and Middle-Income Settings (Prehospital, Emergency Department and Operating Room Setting)|url=https://pubmed.ncbi.nlm.nih.gov/27646281|journal=World Journal of Surgery|volume=41|issue=5|pages=1184–1192|doi=10.1007/s00268-016-3712-x|issn=1432-2323|pmid=27646281}}</ref> RSI with succinylcholine or rocuronium are used for neuromuscular blockade.
 
In patients with an unstable or uncleared cervical spine need in-line stabilization during intubation.  Video Laryngoscopy (VL) may further reduce neck movement during intubation.  


In patients with maxillofacial trauma, airway burns, or penetrating neck injuries, surgical airway may be required. Airway ultrasound may aid in identifying the cricothyroid membrane in challenging scenarios (Pollock et al. 2023).
In patients with maxillofacial trauma, airway burns, or penetrating neck injuries, surgical airway may be required. Airway ultrasound may aid in identifying the cricothyroid membrane in challenging scenarios (Pollock et al. 2023).<ref name=":2" />


=== Positioning<!-- Describe any unique positioning considerations, including potential intraoperative position changes. If none, this section may be removed. --> ===
=== Positioning<!-- Describe any unique positioning considerations, including potential intraoperative position changes. If none, this section may be removed. --> ===
Positioning is dictated by injury and surgical needs, with attention to spinal precautions and pressure point protection.<ref name=":0" /><ref name=":1" />
Positioning should allow for:
* Surgical access
* Hemodynamic optimization
* Prevention of pressure injuries
* Ongoing access to IV lines and monitoring
Trauma patients are often unstable, and movement may precipitate hemodynamic deterioration. Team communication is essential.<ref name=":0" /><ref name=":2" /><ref name=":1" />


=== Maintenance and surgical considerations<!-- Describe the important considerations and general approach to the maintenance of anesthesia, including potential complications. Be sure to include any steps to the surgical procedure that have anesthetic implications. --> ===
=== Maintenance and surgical considerations<!-- Describe the important considerations and general approach to the maintenance of anesthesia, including potential complications. Be sure to include any steps to the surgical procedure that have anesthetic implications. --> ===
Maintenance anesthesia is guided by surgical stage and patient physiology. A typical combination of volatile anesthetics, opioids, and adjuncts (e.g., ketamine infusion) is used as tolerated. Continuous reassessment is essential.  
Maintenance anesthesia is guided by surgical stage and patient physiology. A typical combination of volatile anesthetics, opioids, and adjuncts (e.g., ketamine infusion) is used as tolerated. Continuous reassessment is essential.  


Permissive hypotension (SBP 80–90 mmHg) is accepted in select patients without TBI (Fort & Zack-Guasp 2020). <ref>{{Cite journal|last=Fort|first=Alexander C.|last2=Zack-Guasp|first2=Richard A.|date=2020-03|title=Anesthesia for Patients with Extensive Trauma|url=https://pubmed.ncbi.nlm.nih.gov/32008648|journal=Anesthesiology Clinics|volume=38|issue=1|pages=135–148|doi=10.1016/j.anclin.2019.10.012|issn=1932-2275|pmid=32008648}}</ref>
Permissive hypotension (SBP 80–90 mmHg) is accepted in select patients without TBI (Fort & Zack-Guasp 2020).<ref name=":0" />


Resuscitative endovascular balloon occlusion of the aorta (REBOA) may be used for non-compressible torso hemorrhage (Pollock et al. 2023).
Resuscitative endovascular balloon occlusion of the aorta (REBOA) may be used for non-compressible torso hemorrhage (Pollock et al. 2023).<ref name=":2" />


=== Emergence<!-- List and/or describe any important considerations related to the emergence from anesthesia for this case. --> ===
=== Emergence<!-- List and/or describe any important considerations related to the emergence from anesthesia for this case. --> ===
Line 129: Line 272:


=== Disposition<!-- List and/or describe the postoperative disposition and any special considerations for transport of patients for this case. --> ===
=== Disposition<!-- List and/or describe the postoperative disposition and any special considerations for transport of patients for this case. --> ===
Most poly-trauma patients require ICU-level care postoperatively, especially those with ongoing ventilation, multisystem injuries, or high transfusion requirements. Effective handoff communication is essential for continuity of care (Tobin et al. 2018).
Most poly-trauma patients require ICU-level care postoperatively, especially those with ongoing ventilation, multisystem injuries, or high transfusion requirements. Effective handoff communication is essential for continuity of care (Tobin et al. 2018).<ref name=":1" />


=== Pain management<!-- Describe the expected level of postoperative pain and approaches to pain management for this case. --> ===
=== Pain management<!-- Describe the expected level of postoperative pain and approaches to pain management for this case. --> ===
Line 138: Line 281:
* Ketamine
* Ketamine
* Lidocaine infusion
* Lidocaine infusion
* Regional anesthesia if feasible (Torrie 2022)
* Regional anesthesia if feasible (Torrie 2022)<ref name=":3" /><ref name=":4" />


Chronic pain and opioid dependence are common post-trauma sequelae, so early and adequate pain control is critical.
Chronic pain and opioid dependence are common post-trauma sequelae, so early and adequate pain control is critical.
Line 148: Line 291:
* Acidosis
* Acidosis
* Coagulopathy
* Coagulopathy
*  
*
* Rebleeding
* Rebleeding
* ARDS
* ARDS
Line 160: Line 303:


While core principles remain the same, anesthetic considerations differ across trauma subtypes:
While core principles remain the same, anesthetic considerations differ across trauma subtypes:
* '''Thoracic trauma''': May require lung isolation, PEEP titration, and avoidance of nitrous oxide (Pollock et al. 2023).
* '''Burns''': Anticipate airway edema and hypermetabolic response.
* '''Pelvic fractures''': High risk of hemorrhage; consider early use of REBOA.
* '''TBI''': Maintain normocapnia, avoid hypotension, optimize cerebral perfusion.


{| class="wikitable wikitable-horizontal-scroll"
{| class="wikitable wikitable-horizontal-scroll"
|+
|+
!
|
!Variant 1
|'''Abdominal Trauma'''
!Variant 2
|'''Extremity Trauma'''
|'''Thoracic Trauma'''
|'''Burns'''
|'''Pelvic Fractures'''
|'''TBI'''
|-
|-
|Unique considerations
|'''Unique considerations'''
|
|Hollow viscus or solid organ injury; contamination risk; risk of  abdominal compartment syndrome
|
|Compartment syndrome, tourniquet use, long bone hemorrhage, external  fixator
|May require lung isolation, PEEP titration, and avoidance of nitrous  oxide
|Anticipate airway edema and hypermetabolic response
|High risk of hemorrhage; consider early use of REBOA
|Maintain normocapnia, avoid hypotension, optimize cerebral perfusion
|-
|-
|Position
|'''Position'''
|
|Supine; may require arms tucked and wide exposure
|
|Supine; limb may be prepped/draped independently, traction devices  possible
|Supine with single-lung ventilation setup if needed
|Supine; avoid pressure on burns, special pads if needed
|Supine; pelvic binder or external fixator may be in place
|Supine, head midline, 30° elevation to optimize venous return
|-
|-
|Surgical time
|'''Surgical time'''
|
|Short for damage control, long for definitive repair
|
|Often prolonged if multiple fractures or staged fixation
|Varies depending on injury; may be urgent/emergent
|Often prolonged depending on TBSA and grafting
|Staged procedures often required
|Often combined with other injury repair, timing dependent
|-
|-
|EBL
|'''Estimated Blood Loss (EBL)'''
|
|High risk of major bleeding, especially with liver/spleen injuries
|
|Moderate; varies by fracture severity and soft tissue injury
|Can be significant with vascular or pulmonary vessel injury
|Variable; large TBSA burns may lose significant volume
|Very high, particularly with open or unstable fractures
|Usually minimal unless combined with multisystem trauma
|-
|-
|Postoperative disposition
|'''Postoperative disposition'''
|
|ICU for continued resuscitation, possible second-look laparotomy
|
|Step-down or floor if stable; ICU if polytrauma
|ICU likely for respiratory support and monitoring
|ICU for ventilatory and fluid management, infection monitoring
|ICU for hemodynamic monitoring and ongoing resuscitation
|Neuro ICU; monitor ICP, avoid secondary brain injury
|-
|-
|Pain management
|'''Pain management'''
|
|Multimodal; systemic opioids, epidural rarely used due to coagulopathy
|
|Regional (e.g., femoral or fascia iliaca block) plus systemic meds
|Paravertebral, epidural, or serratus plane blocks; minimize opioids
|IV opioids, ketamine, adjunctive anxiolytics; regional rarely feasible
|Systemic opioids, consider lumbar plexus or LFCN blocks
|IV acetaminophen, opioids with caution; avoid sedation masking exam
|-
|-
|Potential complications
|'''Potential complications'''
|
|Sepsis, multi-organ failure, re-bleeding, abdominal compartment syndrome
|
|Infection, fat embolism, delayed union, neuropathy
|Pneumothorax, hemothorax, respiratory failure
|Airway loss, sepsis, hypothermia, metabolic derangements
|Hemorrhage, coagulopathy, urologic or bowel injury
|Elevated ICP, seizures, neurogenic pulmonary edema
|}
|}



Latest revision as of 10:58, 16 July 2025

Trauma surgery
Anesthesia type

General

Airway

ETT

Lines and access

Large bore PIV (14, 16g), Sheath introducers (Cordis), triple lumen central line, arterial line

Monitors
Primary anesthetic considerations
Preoperative

Full stomach, airway trauma, hypovolemia

Intraoperative

bleeding

Postoperative
Article quality
Editor rating
Unrated
User likes
0

Trauma is a leading cause of death and disability worldwide, particularly in individuals under 45. Anesthetic management of trauma patients requires rapid decision-making, physiologic insight, and close coordination with surgical, emergency, and critical care teams. Hemorrhagic shock remains a primary driver of early mortality, with damage control resuscitation (DCR) principles serving as the cornerstone of early care (Fort & Zack-Guasp 2020).[1] Anesthetic care begins in the trauma bay and extends through the operating room (OR) to the intensive care unit (ICU), requiring continuity and adaptability (Tobin et al. 2018).[2]

Overview

Indications

Trauma surgery under anesthesia is indicated when patients present with injuries requiring emergent or urgent operative intervention, such as:

  • Uncontrolled hemorrhage
  • Hollow viscus or solid organ injury
  • Penetrating trauma
  • Open fractures
  • Vascular compromise
  • Compartment syndrome

Indications for anesthetic involvement extend beyond the OR, often beginning with airway support, hemodynamic resuscitation, and pain management in the emergency department (Pollock et al. 2023).[3]

Surgical procedure

Trauma surgery encompasses a wide range of procedures, from exploratory laparotomy and thoracotomy to damage control orthopedics and vascular repair. Procedures are often staged, with initial operations focused on hemorrhage and contamination control, followed by definitive repair after physiologic stabilization (Tobin et al. 2018).[2]

Preoperative management

Patient evaluation

Initial evaluation follows Advanced Trauma Life Support (ATLS) principles, with a primary survey (ABCDE) to identify and address life-threatening conditions (Fort & Zack-Guasp 2020). [1]

A – Airway with cervical spine protection

  • Assess for patency: look for obstruction, facial trauma, or burns.
  • Intervene with suction, airway adjuncts (e.g., oropharyngeal/nasopharyngeal airway), or definitive airway (endotracheal intubation) as needed.
  • Always assume cervical spine injury in trauma patients; apply cervical collar and maintain manual in-line stabilization during airway maneuvers.

B – Breathing and ventilation

  • Evaluate chest movement, symmetry, respiratory rate, and effort.
  • Auscultate lung fields; identify pneumothorax, hemothorax, or flail chest.
  • Provide oxygen; initiate positive pressure ventilation if inadequate.
  • Consider needle decompression or chest tube for tension pneumothorax or massive hemothorax.

C – Circulation with hemorrhage control

  • Check pulse rate, blood pressure, capillary refill, and skin perfusion.
  • Look for external bleeding; apply direct pressure or tourniquets.
  • Establish two large-bore IVs or intraosseous access.
  • Initiate fluid resuscitation and activate massive transfusion protocol if needed.
  • Perform FAST exam and pelvic X-ray for occult bleeding.

D – Disability (neurologic evaluation)

  • Perform rapid neurologic assessment using the Glasgow Coma Scale (GCS).
  • Check pupillary size and response.
  • Identify signs of traumatic brain injury or spinal cord injury.

E – Exposure and environmental control

  • Fully expose the patient to identify hidden injuries.
  • Prevent hypothermia using warm blankets, warming devices, and warmed IV fluids.
  • Maintain privacy and dignity once life-threatening injuries are excluded.

Neurologic status should be assessed with the Glasgow Coma Scale (GCS). Patients with traumatic brain injury, thoracic trauma, or unstable hemodynamics require special anesthetic consideration.

Component Response Score
Eye Opening Spontaneous 4
To voice 3
To pain 2
No response 1
Verbal Response Oriented 5
Confused 4
Inappropriate words 3
Incomprehensible sounds 2
No response 1
Motor Response Obeys commands 6
Localizes pain 5
Withdraws from pain 4
Abnormal flexion (decorticate) 3
Abnormal extension (decerebrate) 2
No response 1
System Considerations in Trauma and Anesthetic Implications
Airway Facial fractures, airway edema, blood/vomit, cervical spine instability; may require RSI or surgical airway
Neurologic Traumatic brain injury (TBI), spinal cord injury; avoid hypoxia/hypotension, maintain cerebral perfusion, use GCS
Cardiovascular Hemorrhagic shock, tamponade, myocardial contusion; requires volume resuscitation, blood products, vasoactive agents
Pulmonary Pneumothorax, hemothorax, pulmonary contusion, flail chest; manage with chest tubes, lung-protective ventilation
Gastrointestinal Bowel injury, hepatic/splenic laceration; risk of peritonitis, sepsis, rapid deterioration; damage control laparotomy may be needed
Hematologic Coagulopathy (trauma-induced or dilutional), massive transfusion; use balanced ratios, TXA, monitor with TEG/ROTEM
Renal Hypoperfusion, rhabdomyolysis, contrast-induced nephropathy; maintain perfusion, monitor creatinine, avoid nephrotoxins
Endocrine Adrenal insufficiency (especially in chronic steroid users), hyperglycemia; consider stress-dose steroids, tight glucose control
Other Hypothermia, acidosis, electrolyte disturbances (esp. hyperkalemia); actively warm patient, correct derangements, monitor closely
System Considerations
Airway
Neurologic
Cardiovascular
Pulmonary
Gastrointestinal
Hematologic
Renal
Endocrine
Other

Labs and studies

Essential investigations include:

  • Point-of-care labs (ABG, lactate, Hgb)
  • Type and crossmatch
  • Coagulation panel
  • Focused Assessment with Sonography for Trauma (FAST)
  • Chest/pelvis radiographs
  • Extended FAST (E-FAST) including lung and cardiac views (Pollock et al. 2023)[3]

Viscoelastic testing (e.g., TEG/ROTEM/QUANTRA) aids in goal-directed blood product administration during active resuscitation (Pollock et al. 2023).[3]

Operating room setup

Patient preparation and premedication

Premedication is often avoided in unstable trauma patients due to risk of hypotension and hypoventilation. Preoxygenation should be optimized; apneic oxygenation may be used if necessary (Tobin et al. 2018).[2] Anticipate difficult airway and cervical spine precautions.

Regional and neuraxial techniques

Regional anesthesia is increasingly used for trauma, particularly for extremity and rib fractures. Early blockade may improve pain control, decrease opioid exposure, and reduce the risk of chronic pain (Torrie 2022).[4] However, coagulopathy, hypotension, and polytrauma may limit feasibility. Single-shot blocks are preferred in unstable patients (Torrie 2022).[4][5]

Intraoperative management

Monitoring and access

Standard ASA monitors are used, but trauma patients often require:

  • Arterial line (preferably pre-induction)
  • Large-bore IV or intraosseous access
  • Central venous access if volume resuscitation is ongoing
  • Temperature monitoring
  • POCUS or TEE for hemodynamic assessment (Pollock et al. 2023)[3]

Induction and airway management

Rapid sequence induction (RSI) is standard in trauma to mitigate aspiration risk.

Ketamine and etomidate are commonly used induction agents due to hemodynamic stability; propofol is often avoided in hypovolemic patients (Pillay & Hardcastle 2016).[6] RSI with succinylcholine or rocuronium are used for neuromuscular blockade.

In patients with an unstable or uncleared cervical spine need in-line stabilization during intubation. Video Laryngoscopy (VL) may further reduce neck movement during intubation.

In patients with maxillofacial trauma, airway burns, or penetrating neck injuries, surgical airway may be required. Airway ultrasound may aid in identifying the cricothyroid membrane in challenging scenarios (Pollock et al. 2023).[3]

Positioning

Positioning is dictated by injury and surgical needs, with attention to spinal precautions and pressure point protection.[1][2]

Positioning should allow for:

  • Surgical access
  • Hemodynamic optimization
  • Prevention of pressure injuries
  • Ongoing access to IV lines and monitoring

Trauma patients are often unstable, and movement may precipitate hemodynamic deterioration. Team communication is essential.[1][3][2]

Maintenance and surgical considerations

Maintenance anesthesia is guided by surgical stage and patient physiology. A typical combination of volatile anesthetics, opioids, and adjuncts (e.g., ketamine infusion) is used as tolerated. Continuous reassessment is essential.

Permissive hypotension (SBP 80–90 mmHg) is accepted in select patients without TBI (Fort & Zack-Guasp 2020).[1]

Resuscitative endovascular balloon occlusion of the aorta (REBOA) may be used for non-compressible torso hemorrhage (Pollock et al. 2023).[3]

Emergence

Emergence is often delayed in intubated or unstable patients requiring vasopressor support.

If extubation is considered, ensure:

  • Adequate reversal of paralysis
  • Hemodynamic stability
  • Lack of vasopressive agents
  • Full return of airway reflexes
  • Pain well controlled
  • Patient not receiving large volume resuscitation (blood products/crystaloid/colloids)

Otherwise, patients should remain intubated and sedated for ICU transfer.

Postoperative management

Disposition

Most poly-trauma patients require ICU-level care postoperatively, especially those with ongoing ventilation, multisystem injuries, or high transfusion requirements. Effective handoff communication is essential for continuity of care (Tobin et al. 2018).[2]

Pain management

Multimodal analgesia should be used, including:

  • Opioids
  • Acetaminophen, NSAIDs (if renal and bleeding risk acceptable)
  • Ketamine
  • Lidocaine infusion
  • Regional anesthesia if feasible (Torrie 2022)[4][5]

Chronic pain and opioid dependence are common post-trauma sequelae, so early and adequate pain control is critical.

Potential complications

Trauma "Triad of Death:"

  • Hypothermia
  • Acidosis
  • Coagulopathy
  • Rebleeding
  • ARDS
  • Acute kidney injury
  • Sepsis
  • Chronic pain and opioid dependence

Procedure variants

While core principles remain the same, anesthetic considerations differ across trauma subtypes:

Abdominal Trauma Extremity Trauma Thoracic Trauma Burns Pelvic Fractures TBI
Unique considerations Hollow viscus or solid organ injury; contamination risk; risk of abdominal compartment syndrome Compartment syndrome, tourniquet use, long bone hemorrhage, external fixator May require lung isolation, PEEP titration, and avoidance of nitrous oxide Anticipate airway edema and hypermetabolic response High risk of hemorrhage; consider early use of REBOA Maintain normocapnia, avoid hypotension, optimize cerebral perfusion
Position Supine; may require arms tucked and wide exposure Supine; limb may be prepped/draped independently, traction devices possible Supine with single-lung ventilation setup if needed Supine; avoid pressure on burns, special pads if needed Supine; pelvic binder or external fixator may be in place Supine, head midline, 30° elevation to optimize venous return
Surgical time Short for damage control, long for definitive repair Often prolonged if multiple fractures or staged fixation Varies depending on injury; may be urgent/emergent Often prolonged depending on TBSA and grafting Staged procedures often required Often combined with other injury repair, timing dependent
Estimated Blood Loss (EBL) High risk of major bleeding, especially with liver/spleen injuries Moderate; varies by fracture severity and soft tissue injury Can be significant with vascular or pulmonary vessel injury Variable; large TBSA burns may lose significant volume Very high, particularly with open or unstable fractures Usually minimal unless combined with multisystem trauma
Postoperative disposition ICU for continued resuscitation, possible second-look laparotomy Step-down or floor if stable; ICU if polytrauma ICU likely for respiratory support and monitoring ICU for ventilatory and fluid management, infection monitoring ICU for hemodynamic monitoring and ongoing resuscitation Neuro ICU; monitor ICP, avoid secondary brain injury
Pain management Multimodal; systemic opioids, epidural rarely used due to coagulopathy Regional (e.g., femoral or fascia iliaca block) plus systemic meds Paravertebral, epidural, or serratus plane blocks; minimize opioids IV opioids, ketamine, adjunctive anxiolytics; regional rarely feasible Systemic opioids, consider lumbar plexus or LFCN blocks IV acetaminophen, opioids with caution; avoid sedation masking exam
Potential complications Sepsis, multi-organ failure, re-bleeding, abdominal compartment syndrome Infection, fat embolism, delayed union, neuropathy Pneumothorax, hemothorax, respiratory failure Airway loss, sepsis, hypothermia, metabolic derangements Hemorrhage, coagulopathy, urologic or bowel injury Elevated ICP, seizures, neurogenic pulmonary edema

References

  1. 1.0 1.1 1.2 1.3 1.4 Fort, Alexander C.; Zack-Guasp, Richard A. (2020-03). "Anesthesia for Patients with Extensive Trauma". Anesthesiology Clinics. 38 (1): 135–148. doi:10.1016/j.anclin.2019.10.012. ISSN 1932-2275. PMID 32008648. Check date values in: |date= (help)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Tobin, Joshua M.; Barras, William P.; Bree, Stephen; Williams, Necia; McFarland, Craig; Park, Claire; Steinhiser, David; Stone, R. Craig; Stockinger, Zsolt (2018-09-01). "Anesthesia for Trauma Patients". Military Medicine. 183 (suppl_2): 32–35. doi:10.1093/milmed/usy062. ISSN 1930-613X. PMID 30189066.
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Pollock, Gabriel A.; Lo, Jessie; Chou, Henry; Kissen, Michael S.; Kim, Michelle; Zhang, Vida; Betz, Alexander; Perlman, Ryan (2023-01). "Advanced diagnostic and therapeutic techniques for anaesthetists in thoracic trauma: an evidence-based review". British Journal of Anaesthesia. 130 (1): e80–e91. doi:10.1016/j.bja.2022.07.005. ISSN 1471-6771. PMID 36096943 Check |pmid= value (help). Check date values in: |date= (help)
  4. 4.0 4.1 4.2 Torrie, Arissa M. (2022-10-01). "Regional anesthesia and analgesia for trauma: an updated review". Current Opinion in Anaesthesiology. 35 (5): 613–620. doi:10.1097/ACO.0000000000001172. ISSN 1473-6500. PMID 36044292 Check |pmid= value (help).
  5. 5.0 5.1 Saranteas, Theodosios; Koliantzaki, Iosifina; Savvidou, Olga; Tsoumpa, Marina; Eustathiou, Georgia; Kontogeorgakos, Vasileios; Souvatzoglou, Rizos (2019-07). "Acute pain management in trauma: anatomy, ultrasound-guided peripheral nerve blocks and special considerations". Minerva Anestesiologica. 85 (7): 763–773. doi:10.23736/S0375-9393.19.13145-8. ISSN 1827-1596. PMID 30735016. Check date values in: |date= (help)
  6. Pillay, Leressè; Hardcastle, Timothy (2017-05). "Collective Review of the Status of Rapid Sequence Intubation Drugs of Choice in Trauma in Low- and Middle-Income Settings (Prehospital, Emergency Department and Operating Room Setting)". World Journal of Surgery. 41 (5): 1184–1192. doi:10.1007/s00268-016-3712-x. ISSN 1432-2323. PMID 27646281. Check date values in: |date= (help)