Difference between revisions of "Remimazolam"
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Remimazolam is an ultra-short acting benzodiazepine. It possesses the same sedative effects as other benzodiazepines but is metabolized by plasma esterase, allowing it to be titrated for procedural sedation cases. Its use for broader scope (general anesthesia) is being investigated. | |||
==Uses<!-- Describe uses of the drug. If appropriate, add subsections for each indication. -->== | ==Uses<!-- Describe uses of the drug. If appropriate, add subsections for each indication. -->== | ||
Initial trials have proven to be successful for bronchoscopy, upper endoscopy, and colonoscopy. It is FDA approved in the US for all procedural sedation. Its use is actively being studied for other indications as well including general anesthesia induction/maintenance and long-term sedation. | |||
==Contraindications<!-- List contraindications and precautions for use of the drug. -->== | ==Contraindications<!-- List contraindications and precautions for use of the drug. -->== | ||
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===Absolute contraindications<!-- List absolute contraindications for use of the drug. If none, this section may be removed. -->=== | ===Absolute contraindications<!-- List absolute contraindications for use of the drug. If none, this section may be removed. -->=== | ||
* Dextran 40 allergy | |||
* Severe hepatic dysfunction | |||
==Pharmacology== | ==Pharmacology== | ||
Latest revision as of 08:37, 7 May 2025
Remimazolam
| Trade names |
Byfavo |
|---|---|
| Clinical data | |
| Drug class |
Sedative hypnotic |
| Uses |
Sedation |
| Routes of administration |
Intravenous |
| Dosage | |
|
Adult dosing
|
|
| Pharmacodynamics | |
| Mechanism of action |
GABA agonism |
| Pharmacokinetics | |
| Physical and chemical data | |
| Article quality | |
| Editor rating | |
| User likes | 0 |
Remimazolam is an ultra-short acting benzodiazepine. It possesses the same sedative effects as other benzodiazepines but is metabolized by plasma esterase, allowing it to be titrated for procedural sedation cases. Its use for broader scope (general anesthesia) is being investigated.
Uses
Initial trials have proven to be successful for bronchoscopy, upper endoscopy, and colonoscopy. It is FDA approved in the US for all procedural sedation. Its use is actively being studied for other indications as well including general anesthesia induction/maintenance and long-term sedation.
Contraindications
Absolute contraindications
- Dextran 40 allergy
- Severe hepatic dysfunction
Pharmacology
Pharmacodynamics
Mechanism of action
Adverse effects
Pharmacokinetics
Chemistry and formulation
History
References
Top contributors: Chris Rishel and Tony Wang