(Created page with "Barbiturates are GABA agonists. == Contraindications == === Acute intermittent porphyria === Barbiturates stimulate synthesis of ''aminolevulinic acid synthetase'', which is the rate limiting enzyme in the formation of porphyrin. In AIP, defective ''porphobilinogen'' ''deaminase'' causes buildup of porphobilinogen.")
(No difference)

Revision as of 16:51, 9 November 2023

Barbiturates are GABA agonists.

Contraindications

Acute intermittent porphyria

Barbiturates stimulate synthesis of aminolevulinic acid synthetase, which is the rate limiting enzyme in the formation of porphyrin.

In AIP, defective porphobilinogen deaminase causes buildup of porphobilinogen.