Difference between revisions of "Parathyroidectomy"

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{{Infobox surgical case reference
{{Infobox surgical case reference
| anesthesia_type =  
| anesthesia_type = General
| airway =  
| airway = Neuromonitoring ETT
| lines_access =  
| lines_access = PIV
| monitors =  
| monitors = Standard
5-lead ECG
Temperature
Neuromonitoring
| considerations_preoperative =  
| considerations_preoperative =  
| considerations_intraoperative =  
| considerations_intraoperative = Relaxation with remifentanil if neuro monitoring
| considerations_postoperative =  
| considerations_postoperative = Hypocalcemia
}}
Recurrent laryngeal nerve palsy
}}A '''parathyroidectomy''' is the removal of one or more of the parathyroid glands or ectopic glands in patients who have primary hyperparathyroidism. Patients typically present with elevated calcium and associated symptoms of hypercalcemia. For most patients with hyperparathyroidism, only one gland is affected (single adenoma), which allow for minimally invasive parathyroidectomy. However, most procedures are still open parathyroidectomies.


Normal human physiology consists of four parathyroid glands. A parathyroidectomy is the removal of one or more of these glands or ectopic glands in patients who have primary hyperparathyroidism. Patients typically present with elevated calcium and associated symptoms of hypercalcemia. For most patients with hyperparathyroidism, only one gland is affected (single adenoma), which allow for minimally invasive parathyroidectomy. However, most procedures are still open parathyroidectomies.
==Preoperative management ==


== Preoperative management ==
===Patient evaluation<!-- Describe the unique and important aspects of preoperative evaluation. Add or remove rows from the systems table as needed. -->===
 
=== Patient evaluation<!-- Describe the unique and important aspects of preoperative evaluation. Add or remove rows from the systems table as needed. --> ===
{| class="wikitable"
{| class="wikitable"
|+
|+
!System
! System
!Considerations
!Considerations
|-
|-
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|Hypertension and tachycardia are common
|Hypertension and tachycardia are common
|-
|-
|Respiratory
|Pulmonary
|Avoid respiratory acidosis, as this worsens hypercalcemia (less calcium bound to albumin)
|Avoid respiratory acidosis, as this worsens hypercalcemia (less calcium bound to albumin)
|-
|-
|Gastrointestinal
| Gastrointestinal
|Hypercalcemia can cause constipation, nausea/vomiting
|Hypercalcemia can cause constipation, nausea/vomiting
|-
|-
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|}
|}


=== Labs and studies<!-- Describe any important labs or studies. Include reasoning to justify the study and/or interpretation of results in the context of this procedure. If none, this section may be removed. --> ===
===Labs and studies<!-- Describe any important labs or studies. Include reasoning to justify the study and/or interpretation of results in the context of this procedure. If none, this section may be removed. --> ===


* EKG
*EKG
* CBC
*CBC
* BMP to evaluate calcium, magnesium, phosphate,  
*BMP to evaluate calcium, magnesium, phosphate,


=== Operating room setup<!-- Describe any unique aspects of operating room preparation. Avoid excessively granular information. Use drug classes instead of specific drugs when appropriate. If none, this section may be removed. --> ===
===Operating room setup<!-- Describe any unique aspects of operating room preparation. Avoid excessively granular information. Use drug classes instead of specific drugs when appropriate. If none, this section may be removed. -->===


=== Patient preparation and premedication<!-- Describe any unique considerations for patient preparation and premedication. If none, this section may be removed. --> ===
===Patient preparation and premedication<!-- Describe any unique considerations for patient preparation and premedication. If none, this section may be removed. -->===
Patients should receive IV fluids and diuresis to control calcium levels.
Patients should receive IV fluids and diuresis to control calcium levels.


Radioactive tracers such as methylene blue or technetium Sestamibi may be administered preoperatively to facilitate detection of parathyroid glands intraoperatively.
Radioactive tracers such as methylene blue or technetium Sestamibi may be administered preoperatively to facilitate detection of parathyroid glands intraoperatively.


=== Regional and neuraxial techniques<!-- Describe any potential regional and/or neuraxial techniques which may be used for this case. If none, this section may be removed. --> ===
===Regional and neuraxial techniques<!-- Describe any potential regional and/or neuraxial techniques which may be used for this case. If none, this section may be removed. --> ===


== Intraoperative management ==
==Intraoperative management ==


=== Monitoring and access<!-- List and/or describe monitors and access typically needed for this case. Please describe rationale for any special monitors or access. --> ===
=== Monitoring and access<!-- List and/or describe monitors and access typically needed for this case. Please describe rationale for any special monitors or access. -->===


* Intraoperative nerve monitoring (IONM) is used by surgeon to avoid injury to recurrent laryngeal nerve
*Intraoperative nerve monitoring (IONM) is used by surgeon to avoid injury to recurrent laryngeal nerve


=== Induction and airway management<!-- Describe the important considerations and general approach to the induction of anesthesia and how the airway is typically managed for this case. --> ===
===Induction and airway management<!-- Describe the important considerations and general approach to the induction of anesthesia and how the airway is typically managed for this case. -->===


=== Positioning<!-- Describe any unique positioning considerations, including potential intraoperative position changes. If none, this section may be removed. --> ===
* NIMS endotracheal tube is used for recurrent laryngeal nerve monitoring
* Preferably use video laryngoscope so surgery team can confirm lead placement


* Supine
=== Positioning<!-- Describe any unique positioning considerations, including potential intraoperative position changes. If none, this section may be removed. -->===
 
*Supine
* Shoulder roll
* Shoulder roll


=== Maintenance and surgical considerations<!-- Describe the important considerations and general approach to the maintenance of anesthesia, including potential complications. Be sure to include any steps to the surgical procedure that have anesthetic implications. --> ===
=== Maintenance and surgical considerations<!-- Describe the important considerations and general approach to the maintenance of anesthesia, including potential complications. Be sure to include any steps to the surgical procedure that have anesthetic implications. -->===
 
*Avoid paralytic for nerve monitoring. Consider remifentanil instead.


*
=== Emergence<!-- List and/or describe any important considerations related to the emergence from anesthesia for this case. -->===


=== Emergence<!-- List and/or describe any important considerations related to the emergence from anesthesia for this case. --> ===
* Ensure smooth emergence with minimal coughing/bucking, as this can cause neck bleeding
** Consider leaving remifentanil on (around 0.05 mcg/kg/min) or extubating deep.


== Postoperative management ==
==Postoperative management==


=== Disposition<!-- List and/or describe the postoperative disposition and any special considerations for transport of patients for this case. --> ===
===Disposition<!-- List and/or describe the postoperative disposition and any special considerations for transport of patients for this case. --> ===
Regular calcium levels to evaluate for postoperative hypocalcemia, which can occur in up to 15% of patients.
Regular calcium levels to evaluate for postoperative hypocalcemia, which can occur in up to 15% of patients.


=== Pain management<!-- Describe the expected level of postoperative pain and approaches to pain management for this case. --> ===
===Pain management<!-- Describe the expected level of postoperative pain and approaches to pain management for this case. -->===


=== Potential complications<!-- List and/or describe any potential postoperative complications for this case. --> ===
===Potential complications<!-- List and/or describe any potential postoperative complications for this case. --> ===


* Symptomatic hypocalcemia
* Symptomatic hypocalcemia
* Neck hematoma is rare but can develop rapidly, resulting airway compromise. Thus it is a surgical emergency requiring prompt takeback.
*Neck hematoma is rare but can develop rapidly, resulting airway compromise. Thus it is a surgical emergency requiring prompt takeback.
* Laryngeal nerve injury  
*Recurrent laryngeal nerve injury, if unilateral, results in a hoarse voice, but if bilateral, can result in obstructed airway requiring emergent tracheostomy


== Procedure variants<!-- This section should only be used for cases with multiple approaches (e.g. Laparoscopic vs. open appendectomy). Otherwise, remove this section. Use this table to very briefly compare and contrast various aspects between approaches. Add or remove rows as needed to maximize relevance. Consider using symbols rather than words when possible (e.g. +, –, additional symbols such as ↑ and ↓ are available using the "Ω" tool in the editor). --> ==
==Procedure variants<!-- This section should only be used for cases with multiple approaches (e.g. Laparoscopic vs. open appendectomy). Otherwise, remove this section. Use this table to very briefly compare and contrast various aspects between approaches. Add or remove rows as needed to maximize relevance. Consider using symbols rather than words when possible (e.g. +, –, additional symbols such as ↑ and ↓ are available using the "Ω" tool in the editor). --> ==


{| class="wikitable"
{| class="wikitable"
|+
|+
!
!
!Variant 1
! Variant 1
!Variant 2
!Variant 2
|-
|-
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|}
|}


== References ==
==References==


[[Category:Surgical procedures]]
[[Category:Surgical procedures]]
[[Category:General surgery]]
[[Category:Endocrine surgery]]

Latest revision as of 06:42, 29 June 2022

Parathyroidectomy
Anesthesia type

General

Airway

Neuromonitoring ETT

Lines and access

PIV

Monitors

Standard 5-lead ECG Temperature Neuromonitoring

Primary anesthetic considerations
Preoperative
Intraoperative

Relaxation with remifentanil if neuro monitoring

Postoperative

Hypocalcemia Recurrent laryngeal nerve palsy

Article quality
Editor rating
In development
User likes
0

A parathyroidectomy is the removal of one or more of the parathyroid glands or ectopic glands in patients who have primary hyperparathyroidism. Patients typically present with elevated calcium and associated symptoms of hypercalcemia. For most patients with hyperparathyroidism, only one gland is affected (single adenoma), which allow for minimally invasive parathyroidectomy. However, most procedures are still open parathyroidectomies.

Preoperative management

Patient evaluation

System Considerations
Neurologic Hypercalcemia can cause altered mental status, weakness, myalgia, and rarely seizures
Cardiovascular Hypertension and tachycardia are common
Pulmonary Avoid respiratory acidosis, as this worsens hypercalcemia (less calcium bound to albumin)
Gastrointestinal Hypercalcemia can cause constipation, nausea/vomiting
Hematologic
Renal Hypercalcemia can cause polyuria/polydipsia resulting in other electrolyte abnormalities. Also increased risk for nephrolithiasis
Endocrine
Other

Labs and studies

  • EKG
  • CBC
  • BMP to evaluate calcium, magnesium, phosphate,

Operating room setup

Patient preparation and premedication

Patients should receive IV fluids and diuresis to control calcium levels.

Radioactive tracers such as methylene blue or technetium Sestamibi may be administered preoperatively to facilitate detection of parathyroid glands intraoperatively.

Regional and neuraxial techniques

Intraoperative management

Monitoring and access

  • Intraoperative nerve monitoring (IONM) is used by surgeon to avoid injury to recurrent laryngeal nerve

Induction and airway management

  • NIMS endotracheal tube is used for recurrent laryngeal nerve monitoring
  • Preferably use video laryngoscope so surgery team can confirm lead placement

Positioning

  • Supine
  • Shoulder roll

Maintenance and surgical considerations

  • Avoid paralytic for nerve monitoring. Consider remifentanil instead.

Emergence

  • Ensure smooth emergence with minimal coughing/bucking, as this can cause neck bleeding
    • Consider leaving remifentanil on (around 0.05 mcg/kg/min) or extubating deep.

Postoperative management

Disposition

Regular calcium levels to evaluate for postoperative hypocalcemia, which can occur in up to 15% of patients.

Pain management

Potential complications

  • Symptomatic hypocalcemia
  • Neck hematoma is rare but can develop rapidly, resulting airway compromise. Thus it is a surgical emergency requiring prompt takeback.
  • Recurrent laryngeal nerve injury, if unilateral, results in a hoarse voice, but if bilateral, can result in obstructed airway requiring emergent tracheostomy

Procedure variants

Variant 1 Variant 2
Unique considerations
Position
Surgical time
EBL
Postoperative disposition
Pain management
Potential complications

References