MediaWiki:Gadget-calculator-neuro.js
From WikiAnesthesia
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( function() {
mw.calculators.addUnitsBases( {
temperature: {
toString: function( units ) {
units = units.replace( 'deg', '°' );
return units;
}
}
} );
var gcsEyeResponseOptions = [
'Not testable',
'No eye opening',
'To pain',
'To voice',
'Spontaneous'
];
var gcsVerbalResponseOptions = [
'Not testable',
'Makes no sounds',
'Incomprehensible sounds',
'Inappropriate words',
'Confused',
'Oriented'
];
var gcsMotorResponseOptions = [
'Not testable',
'No movements',
'Extension to pain',
'Flexion to pain',
'Withdrawal from pain',
'Localizes Pain',
'Obeys commands'
];
var avmEloquenceOfAdjacentBrainOptions = [
'Non-eloquent',
'Eloquent'
];
var avmVenousDrainageOptions = [
'Superficial veins only',
'Deep veins'
];
var avmRupturedPresentationOptions = [
'Unruptured',
'Ruptured'
];
var avmNidusCompactnessOptions = [
'Compact',
'Diffuse'
];
mw.calculators.addVariables( {
paCO2: {
name: 'PaCO<sub>2</sub>',
type: 'number',
abbreviation: 'PaCO<sub>2</sub>',
minValue: '20 mmHg',
defaultValue: '40 mmHg',
maxLength: 3,
units: [
'mmHg'
]
},
temperature: {
name: 'Temperature',
type: 'number',
abbreviation: 'Temp',
minValue: '20 degC',
maxValue: '44 degC',
defaultValue: '37 degC',
maxLength: 5,
units: [
'degC',
'degF'
]
},
gcsEyeResponse: {
name: 'Eye response',
type: 'string',
abbreviation: 'Eye',
defaultValue: 'Not testable',
options: gcsEyeResponseOptions
},
gcsVerbalResponse: {
name: 'Verbal response',
type: 'string',
abbreviation: 'Verbal',
defaultValue: 'Not testable',
options: gcsVerbalResponseOptions
},
gcsMotorResponse: {
name: 'Motor response',
type: 'string',
abbreviation: 'Motor',
defaultValue: 'Not testable',
options: gcsMotorResponseOptions
},
avmSize: {
name: 'AVM Size',
type: 'number',
minValue: '0.1 cm',
maxValue: '20 cm',
abbreviation: 'AVM size',
defaultValue: '1 cm',
units: [
'cm'
]
},
avmEloquenceOfAdjacentBrain: {
name: 'Eloquence of adjacent brain',
type: 'string',
abbreviation: 'Eloquence',
defaultValue: 'Non-eloquent',
options: avmEloquenceOfAdjacentBrainOptions
},
avmVenousDrainage: {
name: 'Venous drainage',
type: 'string',
abbreviation: 'Venous drainage',
defaultValue: 'Superficial veins only',
options: avmVenousDrainageOptions
},
avmRupturedPresentation: {
name: 'Ruptured presentation',
type: 'string',
abbreviation: 'Ruptured',
defaultValue: 'No',
options: avmRupturedPresentationOptions
},
avmNidusCompactness: {
name: 'Nidus compactness',
type: 'string',
abbreviation: 'Compactness',
defaultValue: 'No',
options: avmNidusCompactnessOptions
}
} );
// Neuro
mw.calculators.addCalculations( {
brainMass: {
name: 'Brain mass',
data: {
variables: {
optional: [ 'age', 'gender' ]
}
},
digits: 0,
units: 'gwt',
description: 'This calculation will give a more precise estimate of brain mass if age and/or sex are provided.',
references: [
'Dekaban AS. Changes in brain weights during the span of human life: relation of brain weights to body heights and body weights. Ann Neurol. 1978 Oct;4(4):345-56. doi: 10.1002/ana.410040410. PMID: 727739.'
],
calculate: function( data ) {
var age = data.age ? data.age.toNumber( 'yr' ) : null;
var gender = data.gender ? data.gender : null;
var brainMassFemale = 1290;
var brainMassMale = 1450;
if( age !== null ) {
if( age <= 10 / 365 ) {
// <=10 days
brainMassFemale = 360;
brainMassMale = 380;
} else if( age <= 4 * 30 / 365 ) {
// Less than 4 months. This is a gap in the reported data of the paper, so linearly interpolate?
var ageFactor = 1 - ( 4 * 30 / 365 - age ) / ( 4 * 30 / 365 - 10 / 365 );
brainMassFemale = 360 + ageFactor * ( 580 - 360 );
brainMassMale = 380 + ageFactor * ( 640 - 380 );
} else if( age <= 8 * 30 / 365 ) {
// <=8 months
brainMassFemale = 580;
brainMassMale = 640;
} else if( age <= 18 * 30 / 365 ) {
// <=18 months
brainMassFemale = 940;
brainMassMale = 970;
} else if( age <= 30 * 30 / 365 ) {
// <=30 months
brainMassFemale = 1040;
brainMassMale = 1120;
} else if( age <= 43 * 30 / 365 ) {
// <=43 months
brainMassFemale = 1090;
brainMassMale = 1270;
} else if( age <= 5 ) {
brainMassFemale = 1150;
brainMassMale = 1300;
} else if( age <= 7 ) {
brainMassFemale = 1210;
brainMassMale = 1330;
} else if( age <= 9 ) {
brainMassFemale = 1180;
brainMassMale = 1370;
} else if( age <= 12 ) {
brainMassFemale = 1260;
brainMassMale = 1440;
} else if( age <= 15 ) {
brainMassFemale = 1280;
brainMassMale = 1410;
} else if( age <= 18 ) {
brainMassFemale = 1340;
brainMassMale = 1440;
} else if( age <= 21 ) {
brainMassFemale = 1310;
brainMassMale = 1450;
} else if( age <= 30 ) {
brainMassFemale = 1300;
brainMassMale = 1440;
} else if( age <= 40 ) {
brainMassFemale = 1290;
brainMassMale = 1440;
} else if( age <= 50 ) {
brainMassFemale = 1290;
brainMassMale = 1430;
} else if( age <= 55 ) {
brainMassFemale = 1280;
brainMassMale = 1410;
} else if( age <= 60 ) {
brainMassFemale = 1250;
brainMassMale = 1370;
} else if( age <= 65 ) {
brainMassFemale = 1240;
brainMassMale = 1370;
} else if( age <= 70 ) {
brainMassFemale = 1240;
brainMassMale = 1360;
} else if( age <= 75 ) {
brainMassFemale = 1230;
brainMassMale = 1350;
} else if( age <= 80 ) {
brainMassFemale = 1190;
brainMassMale = 1330;
} else if( age <= 85 ) {
brainMassFemale = 1170;
brainMassMale = 1310;
} else {
brainMassFemale = 1140;
brainMassMale = 1290;
}
}
if( gender === 'F' ) {
return brainMassFemale;
} else if( gender === 'M' ) {
return brainMassMale;
} else {
return ( brainMassFemale + brainMassMale ) / 2;
}
}
},
cerebralBloodVolume: {
name: 'Cerebral blood volume',
abbreviation: 'CBV',
data: {
calculations: {
required: [ 'brainMass' ]
}
},
units: 'mL',
description: '4 mL per 100g of brain mass',
references: [
'Tameem A, Krovvidi H, Cerebral physiology, Continuing Education in Anaesthesia Critical Care & Pain, Volume 13, Issue 4, August 2013, Pages 113–118, https://doi.org/10.1093/bjaceaccp/mkt001'
],
calculate: function( data ) {
var brainMass = data.brainMass.toNumber( 'gwt' );
return 4 * brainMass / 100;
}
},
cerebralMetabolicRateFactor: {
name: 'Cerebral metabolic rate factor',
abbreviation: '%CMR',
data: {
variables: {
optional: [ 'temperature' ]
}
},
description: '7% change in CMR for every 1 °C change in temperature',
references: [
'Tameem A, Krovvidi H, Cerebral physiology, Continuing Education in Anaesthesia Critical Care & Pain, Volume 13, Issue 4, August 2013, Pages 113–118, https://doi.org/10.1093/bjaceaccp/mkt001'
],
calculate: function( data ) {
var temperature = data.temperature ? data.temperature.toNumber( 'degC' ) : null;
var cerebralMetabolicRateFactor = 1;
if( temperature ) {
cerebralMetabolicRateFactor += 0.07 * ( temperature - 37 );
}
return cerebralMetabolicRateFactor;
}
},
cerebralMetabolicRateO2: {
name: 'Cerebral metabolic rate (O<sub>2</sub>)',
abbreviation: 'CMRO<sub>2</sub>',
data: {
calculations: {
required: [ 'brainMass', 'cerebralMetabolicRateFactor' ]
},
variables: {
optional: [ 'temperature' ]
}
},
units: 'mL/min',
description: '<ul><li>3 mL O<sub>2</sub>/min per 100g of brain mass</li><li>If temperature is provided, adjusts estimate using 7% change in CMR for every 1 °C change in temperature</li></ul>',
references: [
'Tameem A, Krovvidi H, Cerebral physiology, Continuing Education in Anaesthesia Critical Care & Pain, Volume 13, Issue 4, August 2013, Pages 113–118, https://doi.org/10.1093/bjaceaccp/mkt001'
],
searchData: 'cmro2',
calculate: function( data ) {
// Temperature is included as an optional variable to generate the input.
// It is used by cerebralMetabolicRateFactor, which is an internal calculation not typically shown.
var brainMass = data.brainMass.toNumber( 'gwt' );
var cerebralMetabolicRateFactor = data.cerebralMetabolicRateFactor.toNumber();
return cerebralMetabolicRateFactor * 3 * brainMass / 100;
}
},
cerebralMetabolicRateGlucose: {
name: 'Cerebral metabolic rate (Glucose)',
abbreviation: 'CMR<sub>glu</sub>',
data: {
calculations: {
required: [ 'brainMass', 'cerebralMetabolicRateFactor' ]
}
},
units: 'mg/min',
description: '<ul><li>5 mg glucose/min per 100g of brain mass</li><li>7% change in CMR for every 1 °C change in temperature</li></ul>',
references: [
'Tameem A, Krovvidi H, Cerebral physiology, Continuing Education in Anaesthesia Critical Care & Pain, Volume 13, Issue 4, August 2013, Pages 113–118, https://doi.org/10.1093/bjaceaccp/mkt001'
],
calculate: function( data ) {
var brainMass = data.brainMass.toNumber( 'gwt' );
var cerebralMetabolicRateFactor = data.cerebralMetabolicRateFactor.toNumber();
return cerebralMetabolicRateFactor * 5 * brainMass / 100;
}
},
cerebralBloodFlow: {
name: 'Cerebral blood flow',
abbreviation: 'CBF',
data: {
calculations: {
required: [ 'brainMass', 'cerebralMetabolicRateFactor' ]
},
variables: {
optional: [ 'paCO2' ]
}
},
units: 'mL/min',
description: '<ul><li>50 mL/min per 100g of brain mass.</li><li>Every mmHg in PaCO2 changes CBF by 1.5 mL/min per 100g of brain mass.</li><li>Cerebral blood flow and cerebral metabolic rate are coupled. Factors that alter CMR (e.g. temperature) will proportionally alter CBF.</li>',
references: [
'Tameem A, Krovvidi H, Cerebral physiology, Continuing Education in Anaesthesia Critical Care & Pain, Volume 13, Issue 4, August 2013, Pages 113–118, https://doi.org/10.1093/bjaceaccp/mkt001',
'Brian JE Jr. Carbon dioxide and the cerebral circulation. Anesthesiology. 1998 May;88(5):1365-86. doi: 10.1097/00000542-199805000-00029. PMID: 9605698.'
],
calculate: function( data ) {
var brainMass = data.brainMass.toNumber( 'gwt' );
var cerebralMetabolicRateFactor = data.cerebralMetabolicRateFactor.toNumber();
var paCO2 = data.paCO2.toNumber( 'mmHg' );
var cerebralBloodFlow = cerebralMetabolicRateFactor * 50 * brainMass / 100;
if( paCO2 ) {
// CO2 reductions don't reduce CBF more than 50%
var minCerebralBloodFlow = cerebralBloodFlow / 2;
cerebralBloodFlow += 1.5 * brainMass / 100 * ( paCO2 - 40 );
cerebralBloodFlow = math.max( cerebralBloodFlow, minCerebralBloodFlow );
}
return cerebralBloodFlow;
}
},
glasgowComaScale: {
name: 'Glasgow Coma Scale',
abbreviation: 'Glasgow Coma Scale',
data: {
variables: {
required: [ 'gcsEyeResponse', 'gcsVerbalResponse', 'gcsMotorResponse' ]
}
},
type: 'string',
references: [
'Teasdale G, Jennett B. Assessment of coma and impaired consciousness. A practical scale. Lancet. 1974 Jul 13;2(7872):81-4. doi: 10.1016/s0140-6736(74)91639-0. PMID: 4136544.'
],
calculate: function( data ) {
var gcsEyeResponse = gcsEyeResponseOptions.indexOf( data.gcsEyeResponse );
var gcsVerbalResponse = gcsVerbalResponseOptions.indexOf( data.gcsVerbalResponse );
var gcsMotorResponse = gcsMotorResponseOptions.indexOf( data.gcsMotorResponse );
var gcsScore;
if( !gcsEyeResponse || !gcsVerbalResponse || !gcsMotorResponse ) {
gcsScore = 'Cannot be calculated because one or more components are not testable';
gcsEyeResponse = gcsEyeResponse ? gcsEyeResponse : 'NT';
gcsVerbalResponse = gcsVerbalResponse ? gcsVerbalResponse : 'NT';
gcsMotorResponse = gcsMotorResponse ? gcsMotorResponse : 'NT';
} else {
gcsScore = gcsEyeResponse + gcsVerbalResponse + gcsMotorResponse;
}
var gcsScale = 'E(' + gcsEyeResponse + ') V(' + gcsVerbalResponse + ') M(' + gcsMotorResponse + ')';
var $gcsResult = $( '<div>' , { 'class': 'grid' } ).append(
$( '<div>', { 'class': 'row' } ).append(
$( '<div>', { 'class': 'col' } ).append( 'Glasgow coma score:' ),
$( '<div>', { 'class': 'col' } ).append( gcsScore )
),
$( '<div>', { 'class': 'row' } ).append(
$( '<div>', { 'class': 'col' } ).append( 'Glasgow coma scale:' ),
$( '<div>', { 'class': 'col' } ).append( gcsScale )
)
);
return $gcsResult.html();
}
},
avmSpetlzerMartinGrade: {
name: 'Spetlzer-Martin AVM grading scale',
abbreviation: 'Spetzler-Martin grade',
data: {
variables: {
required: [ 'avmSize', 'avmEloquenceOfAdjacentBrain', 'avmVenousDrainage' ]
}
},
type: 'number',
calculate: function( data ) {
var avmSize = data.avmSize.toNumber( 'cm' );
var avmEloquenceOfAdjacentBrain = data.avmEloquenceOfAdjacentBrain;
var avmVenousDrainage = data.avmVenousDrainage;
var spetzlerMartinGrade = 0;
// AVM size
if( avmSize < 3 ) {
spetzlerMartinGrade += 1;
} else if( avmSize <= 6 ) {
spetzlerMartinGrade += 2;
} else {
spetzlerMartinGrade += 3;
}
// Eloquence of adjacent brain
// 0 no, 1 yes
spetzlerMartinGrade += avmEloquenceOfAdjacentBrainOptions.indexOf( avmEloquenceOfAdjacentBrain );
// Venous drainage
// 0 superficial, 1 deep
spetzlerMartinGrade += avmVenousDrainageOptions.indexOf( avmVenousDrainage );
return spetzlerMartinGrade;
}
},
avmSpetzlerMartinGradeRisk: {
name: 'Spetlzer-Martin AVM grading scale',
abbreviation: 'Spetzler-Martin AVM grade',
data: {
calculations: {
required: [ 'avmSpetlzerMartinGrade' ]
},
variables: {
required: [ 'avmSize', 'avmEloquenceOfAdjacentBrain', 'avmVenousDrainage' ]
}
},
type: 'string',
description: '<p>The Spetzler-Martin AVM grading system predicts the morbidity/mortality risk of surgery using angiographic features</p><ul><li>Size of nidus<ul><li>0: Small (<3 cm)</li><li>1: Medium (3-6 cm)</li><li>2: Large (>6 cm)</li></ul></li><li>Eloquence of adjacent brain area<ul><li>0: Non-eloquent</li><li>1: Eloquent</li></ul></li><li>Venous drainage<ul><li>0: Superficial veins only</li><li>1: Deep veins</li></ul></li></ul>',
references: [
'Spetzler RF, Martin NA. A proposed grading system for arteriovenous malformations. J Neurosurg. 1986 Oct;65(4):476-83. doi: 10.3171/jns.1986.65.4.0476. PMID: 3760956.'
],
calculate: function( data ) {
var spetzlerMartinGrade = data.avmSpetlzerMartinGrade.toNumber();
var spetzlerMartinGradeRisk = math.roman( spetzlerMartinGrade );
if( spetzlerMartinGrade <= 3 ) {
spetzlerMartinGradeRisk += ' (low-to-moderate risk)';
} else {
spetzlerMartinGradeRisk += ' (high-risk)';
}
return spetzlerMartinGradeRisk;
}
},
avmSupplementalGrade: {
name: 'Supplemental AVM grading scale',
abbreviation: 'Supplemental AVM grade',
data: {
variables: {
required: [ 'age', 'avmRupturedPresentation', 'avmNidusCompactness' ]
}
},
type: 'number',
calculate: function( data ) {
var age = data.age ? data.age.toNumber( 'yr' ) : 0;
var avmRupturedPresentation = data.avmRupturedPresentation ? data.avmRupturedPresentation : null;
var avmNidusCompactness = data.avmNidusCompactness ? data.avmNidusCompactness : null;
var supplementalGrade = 0;
// Age
if( age < 20 ) {
supplementalGrade += 1;
} else if( age <= 40 ) {
supplementalGrade += 2;
} else {
supplementalGrade += 3;
}
// Ruptured presentation
// 0 unruptured, 1 ruptured
supplementalGrade += avmRupturedPresentationOptions.indexOf( avmRupturedPresentation );
// Diffuse nidus
// 0 compact, 1 diffuse
supplementalGrade += avmNidusCompactnessOptions.indexOf( avmNidusCompactness );
return supplementalGrade;
}
},
avmSupplementalGradeRisk: {
name: 'Supplemental AVM grading scale',
abbreviation: 'Supplemental AVM grade',
data: {
calculations: {
required: [ 'avmSupplementalGrade' ]
},
variables: {
required: [ 'age', 'avmRupturedPresentation', 'avmNidusCompactness' ]
}
},
type: 'string',
description: '<p>The Supplemental AVM grading system provides additional surgical risk stratification in addition to the Spetzler-Martin grade.</p><ul><li>Age<ul><li>1: <20 yo</li><li>2: 20-40 yo</li><li>3: >40 yo</li></ul></li><li>Ruptured presentation<ul><li>0: Unruptured</li><li>1: Ruptured</li></ul></li><li>Nidus compactness<ul><li>0: Compact</li><li>1: Diffuse</li></ul></li></ul>',
references: [
'Lawton MT, Kim H, McCulloch CE, Mikhak B, Young WL. A supplementary grading scale for selecting patients with brain arteriovenous malformations for surgery. Neurosurgery. 2010 Apr;66(4):702-13; discussion 713. doi: 10.1227/01.NEU.0000367555.16733.E1. PMID: 20190666; PMCID: PMC2847513.'
],
calculate: function( data ) {
var supplementalGrade = data.avmSupplementalGrade.toNumber();
var supplementalGradeRisk = math.roman( supplementalGrade );
if( supplementalGrade <= 3 ) {
supplementalGradeRisk += ' (low-to-moderate risk)';
} else {
supplementalGradeRisk += ' (high-risk)';
}
return supplementalGradeRisk;
}
}
} );
}() );