Naloxone

Naloxone

Trade names	Narcan
Clinical data
Uses	Reversal of opioid agonism
Routes of administration	Intramuscular, Intranasal, Intravenous
Dosage	0.04-0.4 mg IV q2-3min prn
Pharmacodynamics
Mechanism of action	Opioid-receptor antagonism
Adverse effects	Acute opioid withdrawal, hypotension, arrhythmias, pulmonary edema
Pharmacokinetics
Onset of action	1-2 minutes (IV) 2-5 minutes (IM)
Duration of action	30-60 minutes
Metabolism	Hepatic
Elimination half-life	1-1.5 hours
Physical and chemical data
Formula	C19H21NO4
Molar mass	327.380 g/mol
Article quality
Editor rating	In development
User likes	0

Naloxone is an opioid-receptor antagonist which is used for the reversal of opioid overdose.