Esophagectomy

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Esophagectomy
Anesthesia type

General

Airway

DLT / SLT + Bronchial blocker

Lines and access

Large bore PIV NGT Arterial Line

Monitors

Standard monitors Invasive hemdynamic +/- Flowtrac

Primary anesthetic considerations
Preoperative
Intraoperative

One-lung ventilation

Postoperative

Aspiration Vocal cord paresis Recurrent laryngeal nerve injury Operative mortality

Article quality
Editor rating
In development
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An esophagectomy remains a formidable surgery with high morbidity and mortality.[1] It is performed for esophageal cancer[2] and non-malignant conditions including hiatal hernias, severe GERD refractory to medical management, esophageal strictures and diverticula, and dysmotility disorders such as achalasia.[1] Anesthetic management may contribute to the improvement of perioperative outcomes; such factors include prevention of tracheal aspiration, lung protective ventilatory strategies, thoracic epidural analgesia, judicious fluid management to optimize tissue oxygen delivery, and attention to issues that may reduce anastomotic complications.[3]

Esophageal cancer incidence has been increasing and is now the eighth most common malignancy worldwide. Despite overall poor prognosis with this malignancy, surgery plays a significant role to increase long-term survival and possible cure. As opposed to traditional open surgerysurgeons have more recently favored minimally invasive, thoracoscopic and laparoscopic approaches including robotic techniques. Minimally invasive approaches allow for direct visualization within the thoracic cavity to reduce chances of injury during dissection and have reduced the pulmonary complications and hastened the recovery period.[4]

Multiple variations of surgical approaches are described in the literature including Ivor Lewis (IL)[5], McKeown, and . Despite the variations, from the anesthesiologist's point of view there are two basic types of esophagectomy:

  1. Transhiatal, chiefly used for tumors in the lower esophagus and GE junction
  2. Combined abdominal/thoracic resection, used for complete esophagectomy and tumors high enough in the esophagus that a thoracic approach must be used for dissection and anastomosis.

Preoperative management

Patient evaluation

System Considerations
Neurologic
Cardiovascular Oxygen consumption increases 50% in the immediate post-op period. Patients need to be able to increase cardiac output and oxygen delivery after surgery.
Respiratory Evaluate smoking history and underlying pulmonary dysfunction
Gastrointestinal Patients have passive reflux following esophagectomy.
Hematologic Hypercoagulability due to malignancy
Renal Underlying renal insufficiency which may be exacerbated
Other

Labs and studies

Operating room setup

Patient preparation and premedication

Regional and neuraxial techniques

  • Thoracic epidural

Intraoperative management

Monitoring and access

  • Invasive hemodynamic monitoring
  • Large bore IV access

Induction and airway management

  • May consider RSI if high-aspiration risk due to esophageal tumor obstructing food passage
  • Left sided double lumen tube or single lumen ETT with bronchial blocker for one lung ventilation

Positioning

  • Ivor Lewis: Start supine position for abdominal thorascopic approach and change to left lateral decubitus for thoracic anastamosis
  • Transhiatal: Supine

Maintenance and surgical considerations

Abdominal Dissection

  • Pt is placed supine and peritoneal cavity is examined for metastatic disease
  • Lower portion of the stomach is mobilized
  • Gastric conduit formed
  • A cervical anastomosis is performed and esophagus and stomach returned to mediastinum

Emergence

Postoperative management

Disposition

  • ICU
  • Step-down unit for Enhanced-Recovery cases

Pain management

  • Epidural management

Potential complications

  1. Anastomotic leak
  2. Vocal cord paresis
  3. Recurrent laryngeal nerve injury
  4. Post-operative atrial fibrillation[6]
  5. Morbidity requiring re-operation
  6. Mortality

Procedure variants

Open Thoracoscopic Robotic Ivor Lewis McKeown Transhiatal
Unique considerations
Position
Surgical time
EBL
Postoperative disposition
Pain management
Potential complications

References

  1. 1.0 1.1 Ng, Ju-Mei (2008-06). "Perioperative Anesthetic Management for Esophagectomy". Anesthesiology Clinics. 26 (2): 293–304. doi:10.1016/j.anclin.2008.01.004. ISSN 1932-2275. Check date values in: |date= (help)
  2. Napier, Kyle J (2014). "Esophageal cancer: A Review of epidemiology, pathogenesis, staging workup and treatment modalities". World Journal of Gastrointestinal Oncology. 6 (5): 112. doi:10.4251/wjgo.v6.i5.112. ISSN 1948-5204. PMC 4021327. PMID 24834141.CS1 maint: PMC format (link)
  3. Jaeger, J. Michael; Collins, Stephen R.; Blank, Randal S. (2012-12). "Anesthetic Management for Esophageal Resection". Anesthesiology Clinics. 30 (4): 731–747. doi:10.1016/j.anclin.2012.08.005. ISSN 1932-2275. Check date values in: |date= (help)
  4. Mariette, Christophe; Markar, Sheraz R.; Dabakuyo-Yonli, Tienhan S.; Meunier, Bernard; Pezet, Denis; Collet, Denis; D'Journo, Xavier B.; Brigand, Cécile; Perniceni, Thierry; Carrère, Nicolas; Mabrut, Jean-Yves (2019-01-10). "Hybrid Minimally Invasive Esophagectomy for Esophageal Cancer". The New England Journal of Medicine. 380 (2): 152–162. doi:10.1056/NEJMoa1805101. ISSN 1533-4406. PMID 30625052.
  5. Lewis, I. (1946-07). "The surgical treatment of carcinoma of the oesophagus; with special reference to a new operation for growths of the middle third". The British Journal of Surgery. 34: 18–31. doi:10.1002/bjs.18003413304. ISSN 0007-1323. PMID 20994128. Check date values in: |date= (help)
  6. Carney, Adam; Dickinson, Matt (2015-03). "Anesthesia for esophagectomy". Anesthesiology Clinics. 33 (1): 143–163. doi:10.1016/j.anclin.2014.11.009. ISSN 1932-2275. PMID 25701933. Check date values in: |date= (help)