Naloxone - Revision history

Chris.Rishel: Added embedded dosage calculation

2022-03-30T07:17:44Z

Added embedded dosage calculation

← Older revision		Revision as of 00:17, 30 March 2022
Line 7:		Line 7:
	\| contraindications =		\| contraindications =
	\| routes = Intramuscular, Intranasal, Intravenous		\| routes = Intramuscular, Intranasal, Intravenous
	\| dosage = ~~Delayed emergence:~~		\| dosage =
	* 20-200 mcg IV q2-3m		\| dosage_calculation = naloxone
	~~Opioid overdose:~~
	* 0.1-2 mg IV/IM/ETT q2-3m
	\| mechanism = μ-opioid antagonism		\| mechanism = μ-opioid antagonism
	\| adverse_effects = Acute opioid withdrawal, hypotension, arrhythmias, pulmonary edema		\| adverse_effects = Acute opioid withdrawal, hypotension, arrhythmias, pulmonary edema

Chris.Rishel at 10:41, 12 November 2021

2021-11-12T10:41:46Z

← Older revision		Revision as of 03:41, 12 November 2021
Line 11:		Line 11:
	Opioid overdose:		Opioid overdose:
	* 0.1-2 mg IV/IM/ETT q2-3m		* 0.1-2 mg IV/IM/ETT q2-3m
	\| mechanism = ~~Opioid~~-~~receptor~~ antagonism		\| mechanism = μ-opioid antagonism
	\| adverse_effects = Acute opioid withdrawal, hypotension, arrhythmias, pulmonary edema		\| adverse_effects = Acute opioid withdrawal, hypotension, arrhythmias, pulmonary edema
	\| time_onset = 1-2 minutes (IV)<br/>2-5 minutes (IM)		\| time_onset = 1-2 minutes (IV)<br/>2-5 minutes (IM)

Chris.Rishel at 09:19, 12 November 2021

2021-11-12T09:19:10Z

← Older revision		Revision as of 02:19, 12 November 2021
Line 7:		Line 7:
	\| contraindications =		\| contraindications =
	\| routes = Intramuscular, Intranasal, Intravenous		\| routes = Intramuscular, Intranasal, Intravenous
	\| dosage = 0.04-~~0.4~~ mg IV q2-~~3min prn~~		\| dosage = Delayed emergence:
			* 20-200 mcg IV q2-3m
			Opioid overdose:
			* 0.1-2 mg IV/IM/ETT q2-3m
	\| mechanism = Opioid-receptor antagonism		\| mechanism = Opioid-receptor antagonism
	\| adverse_effects = Acute opioid withdrawal, hypotension, arrhythmias, pulmonary edema		\| adverse_effects = Acute opioid withdrawal, hypotension, arrhythmias, pulmonary edema

Chris.Rishel at 17:16, 18 February 2021

2021-02-18T17:16:51Z

← Older revision		Revision as of 10:16, 18 February 2021
Line 46:		Line 46:

	== References ==		== References ==
			[[Category:Drug reference]]
			[[Category:Antidotes]]
			[[Category:Opioids]]
			[[Category:Opioid antagonists]]

Chris.Rishel at 16:22, 17 February 2021

2021-02-17T16:22:55Z

← Older revision		Revision as of 09:22, 17 February 2021
Line 10:		Line 10:
	\| mechanism = Opioid-receptor antagonism		\| mechanism = Opioid-receptor antagonism
	\| adverse_effects = Acute opioid withdrawal, hypotension, arrhythmias, pulmonary edema		\| adverse_effects = Acute opioid withdrawal, hypotension, arrhythmias, pulmonary edema
	\| time_onset = 1-2 minutes (IV), 2-5 minutes (IM)		\| time_onset = 1-2 minutes (IV)<br/>2-5 minutes (IM)
	\| duration = 30-60 minutes		\| duration = 30-60 minutes
	\| metabolism = Hepatic		\| metabolism = Hepatic

Chris.Rishel at 16:22, 17 February 2021

2021-02-17T16:22:19Z

← Older revision		Revision as of 09:22, 17 February 2021
Line 21:		Line 21:
	}}		}}

	Naloxone is an opioid-receptor antagonist which is used for the reversal of opioid overdose.		'''Naloxone''' is an opioid-receptor antagonist which is used for the reversal of opioid overdose.

	== Uses<!-- Describe uses of the drug. If appropriate, add subsections for each indication. --> ==		== Uses<!-- Describe uses of the drug. If appropriate, add subsections for each indication. --> ==

Chris.Rishel at 16:20, 17 February 2021

2021-02-17T16:20:41Z

← Older revision		Revision as of 09:20, 17 February 2021
Line 21:		Line 21:
	}}		}}

	~~Provide a brief summary~~ of ~~this drug here~~.		Naloxone is an opioid-receptor antagonist which is used for the reversal of opioid overdose.

	== Uses<!-- Describe uses of the drug. If appropriate, add subsections for each indication. --> ==		== Uses<!-- Describe uses of the drug. If appropriate, add subsections for each indication. --> ==

Chris.Rishel: Created page with "{{Infobox drug reference | trade_names = Narcan | image_file = Naloxone.svg | drug_class = | drug_class_color = opioid_reversal | uses = Reversal of opioid agonism | contrain..."

2021-02-17T16:17:11Z

Created page with "{{Infobox drug reference | trade_names = Narcan | image_file = Naloxone.svg | drug_class = | drug_class_color = opioid_reversal | uses = Reversal of opioid agonism | contrain..."

New page

{{Infobox drug reference
| trade_names = Narcan
| image_file = Naloxone.svg
| drug_class =
| drug_class_color = opioid_reversal
| uses = Reversal of opioid agonism
| contraindications =
| routes = Intramuscular, Intranasal, Intravenous
| dosage = 0.04-0.4 mg IV q2-3min prn
| mechanism = Opioid-receptor antagonism
| adverse_effects = Acute opioid withdrawal, hypotension, arrhythmias, pulmonary edema
| time_onset = 1-2 minutes (IV), 2-5 minutes (IM)
| duration = 30-60 minutes
| metabolism = Hepatic
| halflife_redistribution =
| halflife_elimination = 1-1.5 hours
| clearance =
| protein_binding =
| formula = C19H21NO4
| molar_mass = 327.380 g/mol
}}

Provide a brief summary of this drug here.

== Uses ==

== Contraindications ==

=== Absolute contraindications ===

=== Precautions ===

== Pharmacology ==

=== Pharmacodynamics ===

==== Mechanism of action ====

==== Adverse effects ====

=== Pharmacokinetics ===

== Chemistry and formulation ==

== History ==

== References ==