https://wikianesthesia.org/w/api.php?action=feedcontributions&feedformat=atom&user=Rodonnell 2026-04-04T08:46:01Z User contributions MediaWiki 1.37.1 https://wikianesthesia.org/w/index.php?title=Dexmedetomidine&diff=3806 2022-02-04T04:29:39Z

<p>Rodonnell: </p> <hr /> <div>{{Infobox drug reference<br /> | trade_names = <br /> | image_file = Dexmedetomidine.svg<br /> | drug_class = Sedative hypnotic<br /> | drug_class_color = sedative_hypnotic<br /> | uses = <br /> | contraindications = <br /> | routes = IV, IM, IN<br /> | dosage = <br /> | mechanism = Alpha-2 agonism<br /> | adverse_effects = <br /> | time_onset = <br /> | duration = <br /> | metabolism = <br /> | halflife_redistribution = <br /> | halflife_elimination = <br /> | clearance = <br /> | protein_binding = <br /> }}<br /> <br /> Provide a brief summary of this drug here.<br /> <br /> == Uses&lt;!-- Describe uses of the drug. If appropriate, add subsections for each indication. --&gt; ==<br /> ICU, intra-operative, and procedural sedation without respiratory depression or amnestic properties. May decrease opioid requirement, more so due to sedating rather than analgesic effects.<br /> <br /> ==Contraindications&lt;!-- List contraindications and precautions for use of the drug. --&gt;==<br /> <br /> ===Absolute contraindications&lt;!-- List absolute contraindications for use of the drug. If none, this section may be removed. --&gt;===<br /> <br /> ===Precautions&lt;!-- List precautions for use of the drug. If none, this section may be removed. --&gt;===<br /> <br /> ==Pharmacology==<br /> <br /> ===Pharmacodynamics&lt;!-- Describe the effects of the drug on the body. If appropriate, add subsections by organ system --&gt;===<br /> <br /> ====Mechanism of action&lt;!-- Describe the mechanism of action for the primary uses of the drug. --&gt;====<br /> alpha-2 agonist<br /> <br /> ====Adverse effects&lt;!-- Describe any potential adverse effects of the drug. --&gt;====<br /> Risk of hypotension and bradycardia, in a dose-dependent manner. Night terrors and transient behavioral effects in children have been reported when used for pre-anesthetic sedation, due to calming effects without amnestic properties.<br /> <br /> ===Pharmacokinetics&lt;!-- Describe the pharmacokinetics of the drug. --&gt;===<br /> <br /> ==Chemistry and formulation&lt;!-- Describe the chemistry and formulation of the drug. --&gt;==<br /> <br /> ==History&lt;!-- Describe the historical development of the drug. --&gt;==<br /> <br /> ==References==<br /> <br /> [[Category:Drug reference]]<br /> [[Category:Sedative hypnotics]]</div>

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