https://wikianesthesia.org/w/api.php?action=feedcontributions&feedformat=atom&user=Georgetye 2026-05-27T00:16:15Z User contributions MediaWiki 1.37.1 https://wikianesthesia.org/w/index.php?title=Barbiturates&diff=15872 2023-11-10T00:51:00Z

<p>Georgetye: Created page with &quot;Barbiturates are GABA agonists. == Contraindications == === Acute intermittent porphyria === Barbiturates stimulate synthesis of ''aminolevulinic acid synthetase'', which is the rate limiting enzyme in the formation of porphyrin. In AIP, defective ''porphobilinogen'' ''deaminase'' causes buildup of porphobilinogen.&quot;</p> <hr /> <div>Barbiturates are GABA agonists.<br /> <br /> == Contraindications ==<br /> <br /> === Acute intermittent porphyria ===<br /> Barbiturates stimulate synthesis of ''aminolevulinic acid synthetase'', which is the rate limiting enzyme in the formation of porphyrin.<br /> <br /> In AIP, defective ''porphobilinogen'' ''deaminase'' causes buildup of porphobilinogen.</div>

Georgetye https://wikianesthesia.org/w/index.php?title=Strong_ion_difference&diff=15871 2023-11-10T00:58:47Z

<p>Georgetye: Created page with &quot;Also known as the urine anion gap. SID = Na&lt;sup&gt;+&lt;/sup&gt; + K&lt;sup&gt;+&lt;/sup&gt; - Cl&lt;sup&gt;-&lt;/sup&gt;&quot;</p> <hr /> <div>Also known as the urine anion gap.<br /> <br /> SID = Na&lt;sup&gt;+&lt;/sup&gt; + K&lt;sup&gt;+&lt;/sup&gt; - Cl&lt;sup&gt;-&lt;/sup&gt;</div>

Georgetye https://wikianesthesia.org/w/index.php?title=Xenon&diff=15870 2023-11-10T01:00:02Z

<p>Georgetye: </p> <hr /> <div>{{Infobox drug reference<br /> | trade_names = <br /> | drug_class = Inhalational anesthetic<br /> | drug_class_color = <br /> | uses = Induction and maintenance of anesthesia<br /> | contraindications = <br /> | routes = Inhalational<br /> | dosage = <br /> }}Provide a brief summary of this drug here.<br /> <br /> == Uses &lt;!-- Describe uses of the drug. If appropriate, add subsections for each indication. --&gt; ==<br /> <br /> == Contraindications &lt;!-- List contraindications and precautions for use of the drug. --&gt;==<br /> <br /> === Absolute contraindications &lt;!-- List absolute contraindications for use of the drug. If none, this section may be removed. --&gt; ===<br /> <br /> === Precautions &lt;!-- List precautions for use of the drug. If none, this section may be removed. --&gt; ===<br /> <br /> == Pharmacology ==<br /> <br /> === Pharmacodynamics &lt;!-- Describe the effects of the drug on the body. If appropriate, add subsections by organ system --&gt; ===<br /> <br /> ==== Mechanism of action &lt;!-- Describe the mechanism of action for the primary uses of the drug. --&gt; ====<br /> NMDA antagonist<br /> <br /> ==== Adverse effects &lt;!-- Describe any potential adverse effects of the drug. --&gt; ====<br /> <br /> === Pharmacokinetics &lt;!-- Describe the pharmacokinetics of the drug. --&gt; ===<br /> <br /> == Chemistry and formulation &lt;!-- Describe the chemistry and formulation of the drug. --&gt; ==<br /> <br /> == History &lt;!-- Describe the historical development of the drug. --&gt;==<br /> <br /> == References ==<br /> <br /> [[Category:Drug reference]]</div>

Georgetye https://wikianesthesia.org/w/index.php?title=Thiopental&diff=15869 2023-11-10T00:45:09Z

<p>Georgetye: </p> <hr /> <div>{{Infobox drug reference<br /> | trade_names = <br /> | drug_class = Sedative hypnotic<br /> | drug_class_color = sedative_hypnotic<br /> | uses = Induction of anesthesia<br /> | contraindications = <br /> | routes = <br /> | dosage = <br /> | halflife_redistribution = <br /> | protein_binding = <br /> | clearance = <br /> | halflife_elimination = <br /> | adverse_effects = <br /> | metabolism = <br /> | duration = <br /> | time_onset = <br /> | dosage_calculation = thiopental<br /> | mechanism = GABA&lt;sub&gt;A&lt;/sub&gt; agonism<br /> | image_file = Thiopental.svg<br /> }}<br /> <br /> Barbiturate<br /> <br /> ==Uses&lt;!-- Describe uses of the drug. If appropriate, add subsections for each indication. --&gt;==<br /> Originally was the most common induction agent prior to the introduction of propofol. Thiopental fell out of favor due to it's long context-sensitive half time, which made it difficult to properly time efficient emergence from anesthesia.<br /> <br /> ==Contraindications&lt;!-- List contraindications and precautions for use of the drug. --&gt;==<br /> <br /> ===Absolute contraindications&lt;!-- List absolute contraindications for use of the drug. If none, this section may be removed. --&gt;===<br /> <br /> ===Precautions&lt;!-- List precautions for use of the drug. If none, this section may be removed. --&gt;===<br /> <br /> ==Pharmacology==<br /> <br /> ===Pharmacodynamics&lt;!-- Describe the effects of the drug on the body. If appropriate, add subsections by organ system --&gt;===<br /> <br /> ====Mechanism of action&lt;!-- Describe the mechanism of action for the primary uses of the drug. --&gt;====<br /> <br /> ====Adverse effects&lt;!-- Describe any potential adverse effects of the drug. --&gt;====<br /> <br /> ===Pharmacokinetics&lt;!-- Describe the pharmacokinetics of the drug. --&gt;===<br /> <br /> ==Chemistry and formulation&lt;!-- Describe the chemistry and formulation of the drug. --&gt;==<br /> <br /> ==History&lt;!-- Describe the historical development of the drug. --&gt;==<br /> <br /> ==References==<br /> <br /> [[Category:Drug reference]]<br /> [[Category:General anesthetics]]<br /> [[Category:Intravenous anesthetics]]</div>

Georgetye